From: Biochemical interaction of anti-HCV telaprevir with the ABC transporters P-glycoprotein and breast cancer resistance protein
Vmax(pmol/mg/10 min)
Ki(μmol/L)
No inhibitor
With 50 μmol/L telaprevir
E1S
37.5
41.2
44.4
MTX
4.9
4.6
94.8