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Figure 3 | BMC Research Notes

Figure 3

From: Immunoglobulin A nephropathy with massive paramesangial deposits caused by anti-vascular endothelial growth factor therapy for metastatic rectal cancer: a case report and review of the literature

Figure 3

Light and electron microscopy findings at the second biopsy. (A) Mild mesangial proliferation was seen, but neither definite paramesangial hemispherical deposits nor widened subendothelial spaces were evident. (B) Two glomeruli showed mild mesangial proliferation. However, two glomeruli were globally sclerotic and one had collapsed (ten o’clock position); in addition, tubular atrophy and interstitial fibrosis was evident around these glomeruli. (C) The degree of IgA deposition had clearly decreased compared with the first biopsy. (D) Electron-dense deposits in the mesangium and subendothelial area were obviously decreased compared with the first biopsy. (A) Periodic acid-Schiff (PAS) staining; original magnification 300×. (B) Elastica Masson staining; original magnification 100×.

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BMC Research Notes

ISSN: 1756-0500

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