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Table 4 Efficacy of AED regimen (n = 854)

From: Antiepileptic drug utilization in Bangladesh: experience from Dhaka Medical College Hospital

AED regimen Retention rate At the end of F/U (%/ number of patients) P value Seizure free At the end of F/U (%/ Number of patients) P value
CBZ 91 (287/318)   96 (275/287)  
VPA 86 (154/179)   95 (146/154)  
PHB 22 (15/ 68)   98 (14/15)  
PHT 29 (5/ 17)   100 (5/5)  
CBZ + VPA 100 (115/115)   96 (110/115)  
CBZ + PHB 88 (30/34) <0.001 90 (27/30) <0.001
CBZ + PHT 65 (17/26)   76 (13/17)  
VPA + PHB 77 (16/21)   88 (14/16)  
CBZ + VPA + PHT 100 (34/34)   88 (30/34)  
CBZ + PHB + PHT 92 (24/26)   75 (18/24)  
CBZ + VPA + TOP 100 (8/8)   88 (7/8)  
CBZ + VPA + LTG 100 (8/8)   88 (7/8)  
  1. PHB = Phenobarbitone, CBZ = Carbamazepine, VPA = Sodium Valproate, PHT = Phenytoine, TOP = Topiramate, LTG = Lemotrigine.