Computerized tomography scanning of thorax (A, C) and pelvis (B, D) before initiating crizotinib treatment (A, B) and response to crizotinib (C, D). A: Multiple malignant enlarged lymph nodes in mediastinum and bilateral pleural effusion (arrows). B: Malignant enlarged lymph nodes along right iliac vessels (arrow). C: Objective complete response in thorax without new lesions (arrows). D: Partial response with significant regression of metastatic lymph nodes along iliac vessels (arrow).