Figure 4From: Concomitant occurrence of EGFR (epidermal growth factor receptor) and KRAS (V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog) mutations in an ALK (anaplastic lymphoma kinase)-positive lung adenocarcinoma patient with acquired resistance to crizotinib: a case reportKi-ras2 Kirsten rat sarcoma viral oncogene homolog mutation analysis by pyrosequencing. A: V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog wild type codon 12 + 13 in inguinal lymph node metastasis before starting crizotinib treatment B: V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog mutation (G13D; GGC > GAC) in newly appeared inguinal lymph nodal metastasis after 8 months of crizotinib treatment.Back to article page