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Table 2 Analyses of interactions of differentially expressed miRNAs and mRNAs, considering T2D* and GDM* patients

From: Identifying common and specific microRNAs expressed in peripheral blood mononuclear cell of type 1, type 2, and gestational diabetes mellitus patients

mRNA microRNA #DIANAmT #miRanda #miRDB #miRWalk #RNAhybrid #Targetscan
MMP1(⬇) miR-342-3p(⬆) 1 1 0 1 1 1
RASGEF1B(⬇) miR-342-3p(⬆) 1 1 0 1 1 1
SLC6A8(⬇) miR-342-3p(⬆) 1 1 1 1 1 1
EIF1AY(⬆) miR-30b(⬆) 1 1 0 1 1 1
IL1A(⬇) miR-30b(⬆) 1 1 0 0 0 0
ZFY(⬆) miR-30b(⬆) 1 0 0 0 0 0
ZFY(⬆) miR-144(⬆) 1 1 0 1 1 1
EGR3(⬇) miR-140-3p(⬆) 1 1 0 1 1 1
LPAL2(⬆) miR-140-3p(⬆) 0 0 0 1 1 1
RASGEF1B(⬇) miR-140-3p(⬆) 1 1 0 1 1 1
DDX3Y(⬆) miR-451(⬇) 1 1 0 1 0 1
OXTR(⬇) miR-451(⬇) 1 1 0 1 1 1
SETD5(⬆) miR-451(⬇) 1 1 0 1 1 1
EIF1AY(⬆) miR-30e(⬆) 1 1 1 1 1 1
IL1A(⬇) miR-30e(⬆) 1 1 1 1 1 1
ZFY(⬆) miR-30e(⬆) 1 1 1 1 1 1
EGR3(⬇) miR-142-5p(⬆) 1 1 0 1 1 1
EIF1AY(⬆) miR-142-5p(⬆) 1 1 0 1 1 1
GYPA(⬇) miR-142-5p(⬆) 1 1 0 1 1 1
OR51E2(⬇) miR-142-5p(⬆) 1 1 0 1 1 1
MMP8(⬇) miR-199a-3p(⬇) 0 1 0 1 0 0
SEZ6L2(⬇) miR-199a-3p(⬇) 0 0 0 1 0 1
B4GALNT3(⬆) miR-199a-3p(⬇) 1 1 0 1 1 0
EIF1AY(⬆) miR-199a-3p(⬇) 1 1 0 1 1 0
OXTR(⬇) miR-378(⬆) 1 1 0 1 1 1
MLYCD(⬆) miR-595(⬇) 1 1 0 1 1 0
OXTR(⬇) miR-595(⬇) 1 1 0 1 1 1
IL1A(⬇) miR-181a(⬆) 1 1 1 1 1 1
OR51E2(⬇) miR-181a(⬆) 1 1 0 1 1 1
SLC6A8(⬇) miR-1268(⬇) 0 1 0 1 1 1
B4GALNT3(⬆) miR-1268(⬇) 0 1 0 1 1 1
GYPA(⬇) miR-181d(⬇) 1 1 1 1 1 1
IL1A(⬇) miR-181d(⬇) 1 1 1 1 1 1
HTRA3(⬇) miR-101(⬆) 1 1 1 1 1 1
C8orf4(⬇) miR-101(⬆) 1 1 1 1 1 1
NR4A1(⬇) miR-486-5p(⬇) 1 0 0 1 1 1
EREG(⬇) miR-142-3p(⬆) 1 1 0 1 1 1
LALBA(⬇) miR-142-3p(⬆) 1 1 0 1 1 1
OR51E2(⬇) miR-142-3p(⬆) 1 1 0 1 1 1
CTTN(⬇) miR-142-3p(⬆) 1 1 0 1 1 1
LALBA(⬇) miR-324-5p(⬆) 1 1 0 1 1 1
ZFY(⬆) miR-144(⬆) 1 1 0 1 1 1
  1. *T2D – type 2 diabetes and GDM – gestational diabetes.
  2. #Algorithms for mRNA/miRNA interactions.
  3. Number 1 represents predicted interaction and number 0 indicates non-predicted interaction.
  4. ⬆ mRNA or miRNA upregulation and ⬇mRNA or miRNA downregulation.