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Table 2 Analyses of interactions of differentially expressed miRNAs and mRNAs, considering T2D* and GDM* patients

From: Identifying common and specific microRNAs expressed in peripheral blood mononuclear cell of type 1, type 2, and gestational diabetes mellitus patients

mRNA

microRNA

#DIANAmT

#miRanda

#miRDB

#miRWalk

#RNAhybrid

#Targetscan

MMP1(⬇)

miR-342-3p(⬆)

1

1

0

1

1

1

RASGEF1B(⬇)

miR-342-3p(⬆)

1

1

0

1

1

1

SLC6A8(⬇)

miR-342-3p(⬆)

1

1

1

1

1

1

EIF1AY(⬆)

miR-30b(⬆)

1

1

0

1

1

1

IL1A(⬇)

miR-30b(⬆)

1

1

0

0

0

0

ZFY(⬆)

miR-30b(⬆)

1

0

0

0

0

0

ZFY(⬆)

miR-144(⬆)

1

1

0

1

1

1

EGR3(⬇)

miR-140-3p(⬆)

1

1

0

1

1

1

LPAL2(⬆)

miR-140-3p(⬆)

0

0

0

1

1

1

RASGEF1B(⬇)

miR-140-3p(⬆)

1

1

0

1

1

1

DDX3Y(⬆)

miR-451(⬇)

1

1

0

1

0

1

OXTR(⬇)

miR-451(⬇)

1

1

0

1

1

1

SETD5(⬆)

miR-451(⬇)

1

1

0

1

1

1

EIF1AY(⬆)

miR-30e(⬆)

1

1

1

1

1

1

IL1A(⬇)

miR-30e(⬆)

1

1

1

1

1

1

ZFY(⬆)

miR-30e(⬆)

1

1

1

1

1

1

EGR3(⬇)

miR-142-5p(⬆)

1

1

0

1

1

1

EIF1AY(⬆)

miR-142-5p(⬆)

1

1

0

1

1

1

GYPA(⬇)

miR-142-5p(⬆)

1

1

0

1

1

1

OR51E2(⬇)

miR-142-5p(⬆)

1

1

0

1

1

1

MMP8(⬇)

miR-199a-3p(⬇)

0

1

0

1

0

0

SEZ6L2(⬇)

miR-199a-3p(⬇)

0

0

0

1

0

1

B4GALNT3(⬆)

miR-199a-3p(⬇)

1

1

0

1

1

0

EIF1AY(⬆)

miR-199a-3p(⬇)

1

1

0

1

1

0

OXTR(⬇)

miR-378(⬆)

1

1

0

1

1

1

MLYCD(⬆)

miR-595(⬇)

1

1

0

1

1

0

OXTR(⬇)

miR-595(⬇)

1

1

0

1

1

1

IL1A(⬇)

miR-181a(⬆)

1

1

1

1

1

1

OR51E2(⬇)

miR-181a(⬆)

1

1

0

1

1

1

SLC6A8(⬇)

miR-1268(⬇)

0

1

0

1

1

1

B4GALNT3(⬆)

miR-1268(⬇)

0

1

0

1

1

1

GYPA(⬇)

miR-181d(⬇)

1

1

1

1

1

1

IL1A(⬇)

miR-181d(⬇)

1

1

1

1

1

1

HTRA3(⬇)

miR-101(⬆)

1

1

1

1

1

1

C8orf4(⬇)

miR-101(⬆)

1

1

1

1

1

1

NR4A1(⬇)

miR-486-5p(⬇)

1

0

0

1

1

1

EREG(⬇)

miR-142-3p(⬆)

1

1

0

1

1

1

LALBA(⬇)

miR-142-3p(⬆)

1

1

0

1

1

1

OR51E2(⬇)

miR-142-3p(⬆)

1

1

0

1

1

1

CTTN(⬇)

miR-142-3p(⬆)

1

1

0

1

1

1

LALBA(⬇)

miR-324-5p(⬆)

1

1

0

1

1

1

ZFY(⬆)

miR-144(⬆)

1

1

0

1

1

1

  1. *T2D – type 2 diabetes and GDM – gestational diabetes.
  2. #Algorithms for mRNA/miRNA interactions.
  3. Number 1 represents predicted interaction and number 0 indicates non-predicted interaction.
  4. ⬆ mRNA or miRNA upregulation and ⬇mRNA or miRNA downregulation.