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Figure 1 | BMC Research Notes

Figure 1

From: A systems biology approach for the identification of target genes for the improvement of itaconic acid production in Aspergillus species

Figure 1

Schematic representation of Glycolysis and pentose phosphate pathway . Broad arrows indicate the enzymes (indicated by the names of the corresponding genes) highly related to itaconic acid production as identified from the A. terreus clone based transcriptome data analysis (see Additional file 1: Table S1). Group I (black arrows) pgdA (6-phosphogluconate dehydrogenase), rpeA (ribulose-phosphate 3-epimerase), rpiB (ribose 5-phosphate isomerase), cadA (cis-aconitate decarboxylase), group II (vertically striped arrow) gpdA (glyceraldehyde-3-phosphate dehydrogenase), group III (white arrows) gpdB (glyceraldehyde-3-phosphate dehydrogenase), pppA (transaldolase). The vitamins dependent tklA (transketolase), pycA (pyruvate carboxylase) and pdcA (pyruvate decarboxylase) (thus related to the upregulated vitamin biosynthetic genes in group II and IV) were indicated with the blocked filled arrows.

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BMC Research Notes

ISSN: 1756-0500

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