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Table 5 Analysis of tumor characteristics influencing MALAT1 levels in human blood

From: Evaluation of long noncoding RNA MALAT1 as a candidate blood-based biomarker for the diagnosis of non-small cell lung cancer

   NSCLC AdCa SqCC
   β 95% CI p value β 95% CI p value β 95% CI p value
Intercept   -1.23 -3.49; 1.03      -1.23 -3.41; 0.96  
Tumor size (Reference: I/II) III/IV 1.06 -1.28; 3.39 0.3670     1.52 -0.82; 3.85 0.1911
Intercept   -0.15 -1.11; 0.80   -0.22 -3.24; 2.81   -0.14 1.15; 0.86  
Metastasis status (Reference: M0) M1 -0.14 -1.36; 1.07 0.8143 -0.46 -3.64; 2.72 0.7655 0.65 -0.98; 2.26 0.4158
Intercept   -0.20 -2.48; 2.08   0.24 -4.02; 4.51   -0.42 -3.20; 2.35  
Lymph node status (Reference: N0) N1-N3 -0.04 -2.40; 2.32 0.9714 -0.92 -5.29; 3.45 0.6654 0.57 -2.32; 3.47 0.6860
  1. Values of β > 0 indicate a negative association between the analyzed factor and MALAT1 levels, values < 0 a positive association.