Histopathological appearance and Fluorescense in sith hybridzation analysis. (A) Histopathological analysis of right submandibular biopsy material, stained with hematoxylin and eosin. This image shows numerous apoptotic cells in a so-called ‘starry-sky’ appearance. (B) Fluorescence in situ hybridization study showing positive signals for IgH/MYC, but not IgH/BCL-2. Green indicates IgH, red indicates MYC or BCL-2, and yellow denotes areas where green and red signals coincide.