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Table 1 Estimated average monthly rates of adverse events per 100,000 patients in two time periods

From: Rosiglitazone use and associated adverse event rates in Canada between 2004 and 2010

  April 2004 - October 2007 November 2007 - December 2010
  Average Range 95% CI Average Range 95% CI
Adverse events 13.4 2.3-27.3 8.6-20.8 5.7 0.0-12.5 2.4-13.6
Serious adverse events 6.0 0.6-21.5 3.1-11.5 3.4 0.0-8.7 1.1-10.6
Cardiac adverse events 2.3 0.0-9.4 0.8-6.5 2.2 0.0-6.6 0.5-8.9