Table 1 DNA damage/repair genes which overlap in both datasets with similar fold-change and direction of association
From: DNA repair/replication transcripts are down regulated in patients with Fragile X Syndrome
Gene symbol | p-value | FDR corrected p-value | Fold change(FX vs. con) | Fold-change direction(FX vs. con) |
|---|---|---|---|---|
BRCA2 | 0.004 | 0.01 | −1.17 | down |
CDKN1A | 0.02 | 0.03 | −1.11 | down |
ERCC1 | 0.0003 | 0.04 | −1.06 | down |
FANCC | 0.02 | 0.001 | −1.08 | down |
NUP98 | 0.002 | 0.01 | −1.10 | down |
PSMB1 | 0.02 | 0.02 | −1.04 | down |
PSMD9 | 0.0004 | 0.03 | −1.08 | down |
PSME2 | 0.0001 | 0.008 | −1.07 | down |
PSME3 | 0.0005 | 0.003 | −1.10 | down |
RFC1 | 0.003 | 0.02 | −1.06 | down |
BUB3 | 0.02 | 0.009 | 1.10 | up |
POLB | 0.007 | 0.01 | 1.08 | up |
PPP2R5A | 0.02 | 0.02 | 1.05 | up |
PSMD10 | 0.005 | 0.01 | 1.03 | up |
RAD17 | 0.01 | 0.01 | 1.05 | up |
RANBP2 | 0.03 | 0.05 | 1.04 | up |