Antimicrobial susceptibility of Streptococcus pneumoniae in adult patients with pneumococcal pneumonia in an urban hospital in Mozambique

Table 1 Pneumococcal antimicrobial susceptibility testing results

Strain	Penicillin MIC (mg/L)	Oxacillin zone diameter BI	Erythromycin zone diameter BI	Co-trimoxazole zone diameter BI
1	<0.016	S	S	I
2	<0.016	S	S	S
3	0.016	S	S	R
4	0.016	S	S	I
5	0.016	S	S	S
6	0.016	S	S	I
7	0.016	S	S	I
8	0.023	S	S	S
9	0.047	S	S	R
10	0.047	NS	S	I
11	0.125	NS	S	R
12	0.25	NS	S	R
13	0.75	NS	S	R
14	0.75	NS	S	R
15	0.75	NS	S	R
16	ND	NS	S	I

Minimal inhibitory concentration (MIC) and zone diameter breakpoint interpretation (BI) of cultured pneumococcal strains, as measured by E-test (penicillin) and disc diffusion method (oxacillin, erythromycin, co-trimoxazole), respectively. S: susceptible; NS: non-susceptible; R: resistant. In pneumonia, when a dose of 1.2 g (2 million IU) × 4 is used, isolates with MIC ≤0.5 mg/L should be regarded as susceptible to benzyl penicillin; with a dose of 2.4 g × 4 or 1.3 g × 6, isolates with MIC ≤1 mg/L should be regarded as susceptible; and with a dose of 2.4 g × 6, isolates with MIC ≤2 mg/L should be regarded as susceptible [8]. Not done: ND.

ISSN: 1756-0500