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Table 1 Clinical and pathologic features of the reported cases of intravascular fasciitis

From: Intravascular fasciitis involving the flank of a 21-year-old female: a case report and review of the literature

References # Age (years) and sex Location Gross features Microscopic features IHC features of spindle cells
Patchefsky et al. 1981 [1] 17 20.5 (range from 0.5 to 57), 8 F and 9 M Head and neck (n = 5) 1.5 cm* (range from 0.6 to 5), single, firm, non-tender, immobile mass Feathery, edematous, myxoid, and hyalinized background, giant cells present in 1/3 cases N/A
Upper extremity (n = 7)
Trunk (n = 2)
Lower extremity (n = 3)
Freedman et al. 1986 [3] 2 19, M Right posterior mucobuccal fold 2.5 cm, single, firm mass with ulcer Myxoid and highly vascular background with rare mitotic figures N/A
53, M Left buccal mucosa 2.0 cm, single, firm, immobile mass Myxoid and locally hyalinized background, no mitotic figures present N/A
Kahn et al. 1987 [4] 1 20, F Left lower labial mucosa 1.5 cm, single, firm, immobile mass Myxoid and highly vascular background, giant cells and mitotic figures present N/A
Price et al. 1993 [5] 2 17, M Outer canthus of right eye 2.0 cm, single mass Myxoid background, giant cells and mitotic figures (Less than 1/HPF) present N/A
20, M Subcutis adjacent to eye and beneath orbicularis oculi 1.0 cm, single, firm, non-tender, mobile mass Myxoid background, giant cells and mitotic figures (Less than 1/HPF) present N/A
Samaratunga et al. 1996 [2] 1 49, M Left inguinal region 3.0 cm, single, firm, non-tender mass Myxoid background with cleft-like spaces, giant cells and mitotic figures (2/10 HPF) present (+) Vimentin, SMA
(-) LMWK, S100
Beer et al. 1996 [6] 1 18, F Lateral thigh 2.0 cm, single, tender, mobile mass Focally myxoid and highly vascular background, mitosis present (-) SMA, S100
Sticha et al. 1997 [7] 1 4, M Plantar aspect of right foot 3.0 cm, single, firm, tender, immobile mass Myxomatous and hyalinized background, giant cell and mitosis present N/A
Ito et al. 1999 [8] 1 26, M Flexor side of right forearm Single, tender mass Fibrous and vascular background, giant cells and mitotic figures (up to 1/10 HPF) present (+) Vimentin, SMA
(-) Desmin
Anand et al. 2007 [9] 1 20, F Hypothenar eminence of right hand 3.0 cm, single, firm, non-tender, mobile mass Fibrous background, giant cells and mitotic figures present (+) SMA
(-) S100, desmin
Sugaya et al. 2007 [10] 1 66, M Medial border of right foot 0.3 cm, single, non-tender, mobile mass Myxoid background, no giant cells present, rare mitotic figures (+) Vimentin
(-) SMA, cytokeratin, S100, desmin, CD31, CD34, c-kit
Pantanowitz et al. 2008 [11] 1 17, M Wrist 1.2 cm, single mass N/A N/A
Wang et al. 2009 [12] 1 28, F Left leg Multiple, firm, non-tender masses Myxoid background, no giant cells or mitotic figures present (+) Vimentin, SMA
(-) Ketatin, S100, desmin
Chi et al. 2012 [13] 1 20, F Upper lip 0.5 cm, single, firm, non-tender, mobile mass Giant cells and mitotic figures (11/10 HPF) present (+) SMA
(-) S100
Reiser et al. 2012 [14] 1 58, F Right cheek 1.7 cm, single mass Focally myxoid and highly vascular background, no giant cells present, rare mitotic figures (+) SMA
Focal (+) Bcl-2
(-) Pankeratin, S100, desmin, EMA
Current case, 2013 1 21, F Flank 0.5 cm, single mass Fibrous background, giant cells present with no mitotic figures (+) SMA
Focal (+) muscle specific actin
       (-) S100
  1. *Size in greatest dimension.
  2. EMA: epithelial membrane antigen.
  3. HPF: high power field.
  4. LMWK: low molecular weight keratin.
  5. N/A: not applicable.
  6. SMA: smooth muscle actin.