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Table 1 Prevalence of IL28B genotypes in Hungarian HCV patients and healthy controls

From: IL28B and IL10R −1087 polymorphisms are protective for chronic genotype 1 HCV infection and predictors of response to interferon-based therapy in an East-Central European cohort

IL28B genotype

HCV1 (n = 748)

Controls (n = 105)

OR

CC

195 (26.1%)

54 (51.4%)

0.333 (0.22 - 0.505)

P < 0.001

CT

411 (54.9%)

39 (37.1%)

2.064 (1.354 - 3.145)

p = 0.001

C allele

606 (81.02%)

93 (88.6%)

0.551 (0.294-1.032)

p = 0.059

TT

142 (19.0%)

12 (11.4%)

1.816 (0.969 – 3.404)

p = 0.059

T allele (non-CC)

553 (73.9%)

51 (48.6%)

3.003 (1.981 – 4.552)

   

P < 0.001