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Table 3 Prevalence of IL10R −1087 genotypes in HCV patients and healthy controls

From: IL28B and IL10R −1087 polymorphisms are protective for chronic genotype 1 HCV infection and predictors of response to interferon-based therapy in an East-Central European cohort

IL10R −1087 Genotype

HCV1 (n = 672)

Controls (n = 92)

OR

GG

214 (31.8)

48 (52.2%)

0.428 (0.276 - 0.665)

p < 0.001

GA

333 (49.6%)

32 (34.8%)

1.842 (1.169 – 2.903)

p = 0.008

G allele

547 (81.4%)

80 (87.0%)

0.656 (0.347-1.241)

p = 0.192

AA

125 (18.6%)

12 (13.0%)

1.523 (0.806 – 2.881)

p = 0.192

A allele (non-GG)

458 (68.15%)

44 (47.8%)

2.335 (1.504 – 3.625)

   

p < 0.001