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Table 2 Genotypic combinations of the three genotyped variants related with warfarin, in 148 Greek-Cypriot individuals

From: Genetic polymorphisms in warfarin and tacrolimus-related genes VKORC1, CYP2C9 and CYP3A5 in the Greek-Cypriot population

Genotypic combinations

No

%

VKORC1 -AA

CYP2C9*2/*2

CYP2C9*1/*3

0

0

VKORC1 -AA

CYP2C9*2/*2

CYP2C9*1/*1

2****

1.35

VKORC1 -AA

CYP2C9*1/*2

CYP2C9*1/*3

2****

1.35

VKORC1 -AG

CYP2C9*1/*2

CYP2C9*1/*3

2***

1.35

VKORC1 -AG

CYP2C9*2/*2

CYP2C9*1/*1

3***

2.03

VKORC1 -AA

CYP2C9*1/*2

CYP2C9*1/*1

7***

4.73

VKORC1 -AA

CYP2C9*1/*1

CYP2C9*1/*3

10***

6.76

VKORC1 -AG + GG

CYP2C9*1/*1

CYP2C9*1/*3

19

12.84

VKORC1 -AA

CYP2C9*1/*1

CYP2C9*1/*1

23

15.54

VKORC1 -AG + GG

CYP2C9*1/*2 + *2/*2

CYP2C9*1/*1

25

16.89

VKORC1 -AG + GG

CYP2C9*1/*1

CYP2C9*1/*1

55

37.16

SUM

148

100

  1. No CYP2C9*3/*3 genotypes were observed.
  2. **** Individuals with four risk alleles (2.70%).
  3. *** Individuals with three risk alleles (14.87%).