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Table 2 Genotypic combinations of the three genotyped variants related with warfarin, in 148 Greek-Cypriot individuals

From: Genetic polymorphisms in warfarin and tacrolimus-related genes VKORC1, CYP2C9 and CYP3A5 in the Greek-Cypriot population

Genotypic combinations No %
VKORC1 -AA CYP2C9*2/*2 CYP2C9*1/*3 0 0
VKORC1 -AA CYP2C9*2/*2 CYP2C9*1/*1 2**** 1.35
VKORC1 -AA CYP2C9*1/*2 CYP2C9*1/*3 2**** 1.35
VKORC1 -AG CYP2C9*1/*2 CYP2C9*1/*3 2*** 1.35
VKORC1 -AG CYP2C9*2/*2 CYP2C9*1/*1 3*** 2.03
VKORC1 -AA CYP2C9*1/*2 CYP2C9*1/*1 7*** 4.73
VKORC1 -AA CYP2C9*1/*1 CYP2C9*1/*3 10*** 6.76
VKORC1 -AG + GG CYP2C9*1/*1 CYP2C9*1/*3 19 12.84
VKORC1 -AA CYP2C9*1/*1 CYP2C9*1/*1 23 15.54
VKORC1 -AG + GG CYP2C9*1/*2 + *2/*2 CYP2C9*1/*1 25 16.89
VKORC1 -AG + GG CYP2C9*1/*1 CYP2C9*1/*1 55 37.16
SUM 148 100
  1. No CYP2C9*3/*3 genotypes were observed.
  2. **** Individuals with four risk alleles (2.70%).
  3. *** Individuals with three risk alleles (14.87%).