Changes in serum cytokines in response to musculoskeletal surgical trauma

BMC Research Notes

Table 1 Changes in serum cytokines (pg/mL)

	T1	T2	T3	T4	T5	ANOVA
Il-1Rα	441 ± 118	345 ± 125^a	363 ± 191	398 ± 119	498 ± 189	0.011
Il-2R	231 ± 70	179 ± 66	187 ± 86	231 ± 67	346 ± 29^b	0.003
Il-6	13 ± 33	14 ± 27	33 ± 23^c	41 ± 29^d	22 ± 26	0.008
Il-8	8.9 ± 4.3	10.0 ± 4.7	18.2 ± 22^e	10.4 ± 4.7	15.1 ± 6.4	0.028
Il-12	135 ± 38	106 ± 37^f	100 ± 46^g	111 ± 36	141 ± 67	0.018
Il-16	0.3 ± 0.9	0.6 ± 0.8	1.0 ± 0.7^h	1.2 ± 1.0ⁱ	0.7 ± 0.9	0.010
Eotaxin	66 ± 20	50 ± 25^j	44 ± 26^k	38 ± 18^l	47 ± 16 ^m	0.001

Time points are before induction of anaesthesia (T1), at the end of surgery (T2), at 6 hours after surgery (T3), at the day after surgery (T4), and at 6 days after surgery (T5). Values are mean ± standard deviation.
^ap = 0.044, ^bp = 0.014, ^cp = 0.020, ^dp = 0.003, ^ep = 0.006, ^fp = 0.047, ^gp = 0.018, ^hp = 0.019, ⁱp = 0.002, ^jp = 0.018, ^kp = 0.001 ^lp = <0.001, ^mp = 0.005 in relation to T1.

ISSN: 1756-0500