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Table 2 Changes in serum cytokines (pg/mL)

From: Changes in serum cytokines in response to musculoskeletal surgical trauma

  T1 T2 T3 T4 T5 ANOVA
IL-1β 9.2 ± 20 4.7 ± 12 4.5 ± 12 4.3 ± 13 12 ± 21 0.421
IL-2 3.3 ± 8.3 1.5 ± 3.8 1.3 ± 2.5 1.9 ± 4.9 3.6 ± 7.1 0.969
IL-5 9.3 ± 11 9.2 ± 11 12 ± 11 11 ± 11 9.2 ± 11 0.934
IL-7 22 ± 21 16 ± 20 15 ± 18 19 ± 19 27 ± 20 0.500
IL-10 22 ± 53 16 ± 38 15 ± 42 17 ± 39 16 ± 37 0.989
IL-13 7.8 ± 6.2 6.2 ± 5.9 7.8 ± 6.5 7.7 ± 6..4 8.1 ± 7.3 0.711
IL-15 70 ± 29 60 ± 28 62 ± 29 63 ± 26 81 ± 39 0.175
IL-17 0.6 ± 2.5 0.1 ± 0.2 1.0 ± 3.4 0.1 ± 0.1 1.2 ± 3.5 0.446
TNF-α 0.9 ± 1.7 0.6 ± 1.1 0.6 ± 0.7 0.7 ± 0.9 0.8 ± 1.1 0.947
INF-α 43 ± 21 2 9 ± 21 26 ± 24 36 ± 24 44 ± 21 0.182
INF-γ 15 ± 13 15 ± 14 14 ± 13 14 ± 14 20 ± 15 0.904
GM-CSF 106 ± 223 77 ± 182 4 5 ± 115 80 ± 182 86 ± 183 0.918
MIP-1α 50 ± 22 45 ± 20 44 ± 36 47 ± 22 53 ± 17 0.785
MIP-1β 44 ± 20 42 ± 25 53 ± 37 56 ± 27 55 ± 21 0.356
IP-10 243 ± 139 213 ± 119 214 ± 165 187 ± 128 314 ± 272 0.230
MIG 41 ± 27 27 ± 19 28 ± 28 29 ± 21 35 ± 23 0.361
RANTES 3489 ± 2072 2972 ± 2565 3002 ± 3874 3154 ± 2963 4553 ± 3501 0.607
MCP-1 229 ± 55 199 ± 48 293 ± 112 221 ± 84 248 ± 59 0.147
EGF 1.7 ± 2.8 0.9 ± 1.6 2.8 ± 6.3 1.1 ± 1.6 2.4 ± 2.8 0.368
G-CSF 113 ± 59 89 ± 66 92 ± 99 104 ± 64 119 ± 64 0.603
FGF 18 ± 24 13 ± 24 13 ± 16 14 ± 16 18 ± 16 0.764
HGF 89 ± 27 64 ± 23 114 ± 68 156 ± 96 134 ± 36 0.577
VEGF 3.4 ± 4.0 3.2 ± 3.9 4.1 ± 4.0 3.5 ± 4.2 3.7 ± 3.9 0.949
  1. Time points are before induction of anaesthesia (T1), at the end of surgery (T2), at 6 hours after surgery (T3), at the day after surgery (T4), and at 6 days after surgery (T5). Values are mean ± standard deviation.