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Table 8 Univariate analyses of risk factors for kidney disease and interaction terms; binomial logistic regression

From: Prevalence and risk factors of kidney disease in urban Karachi: baseline findings from a community cohort study

Variables

Kidney diseasea

 

Prevalence odds ratio (95% CI)

p value

Age (for every 1 year increase in age)

1.05 (1.03-1.07)

0.000**

Age groups

  

 40+

4.0 (2.2-7.2)

0.000**

 ≤ 39

Ref

 

HDL

0.96 (0.9-0.99)

0.03*

Gender

  

 Male

1.6 (0.9-2.8)

0.13

 Female

Ref

 

Diabetes mellitus status

  

 Diabetic

2.8 (1.3-6.4)

0.01*

 Non-diabetic

Ref

 

Hypertension status

  

 Hypertensive

2.3 (1.3-4.4)

0.006*

 Normotensive

Ref

 

Smoking status

  

 Regular smoker

2.7 (1.3-5.6)

0.007*

 Non-smoker

Ref

 

Interaction terms

Hypertension and smoking interaction

  

 Normotensive & smoker

2.4 (0.98-5.8)

0.054

 Hypertension & non-smoker

2.2 (1.097-4.4)

0.03*

 Hypertension & smoker

8.9 (2.3-35.2)

0.002*

 Normotensive & non-smoker

Ref

 

Hypertension and diabetes mellitus interaction

  

 Normotensive & diabetic

2.0 (0.6-6.6)

0.2

 Hypertension & non-diabetic

2.0 (1.006-4.1)

0.048*

 Hypertension & diabetic

5.7 (1.8-18.0)

0.003*

 Normotensive & non-diabetic

Ref|

 

Diabetes mellitus and smoking interaction

  

 Non-diabetic & smoker

2.6 (1.2-5.8)

0.02*

 Diabetic & non-smoker

2.7 (1.1-6.9)

0.04*

 Diabetic & smoker

6.5 (1.3-33.4)

0.03*

 Non-diabetic & non-smoker

Ref

 
  1. a. The reference category is: absence of kidney disease.
  2. *p value < 0.05; **p value < 0.0001 calculated by binary logistic regression.
  3. Abbreviations are: CI-Confidence Interval, Ref-reference.