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Table 1 Allele and genotype frequencies of the APOE , MTHFR and ACE polymorphisms and HWE in the Zambian population (n = 116)

From: Frequency of APOE, MTHFR and ACE polymorphisms in the Zambian population

Polymorphism Allele Frequency Genotype % observed % expected HWE
APOE       p = 0.456
Ε2 0.14 Ε2Ε2 0 1.9 X2 = 4.684
Ε3 0.6 Ε3Ε3 32.8 35.4  
Ε4 0.27 Ε4Ε4 7.8 7.1  
   Ε2Ε3 21.6 16.4  
   Ε2Ε4 6 7.4  
   Ε3Ε4 31.9 31.8  
MTHFR C677T       p = 0.540
C 0.91 CC 82.8 83.5 X2 = 1.233
T 0.09 CT 17.2 15.7  
   TT 0 0.74  
ACE D/I       p = 0.005
D 0.14 DD 5 1.9 X2 = 10.472
I 0.86 ID 17.2 23.8  
    II 77.6 74.3