Risk factors | Congenital malformations | Unadjusted | Adjusted | |||
---|---|---|---|---|---|---|
Yes n (%) | No n (%) | OR [95% CI] | P-value | OR [95% CI] | P-value | |
Sex | ||||||
Male | 64 (26.3) | 179 (73.7) | 1 | 1 | ||
Female | 65 (32.5) | 135 (67.5) | 1.3 [0.9-2.0] | 0.156 | 1.8 [1.1-2.8] | 0.013 |
Birth order | ||||||
≤4 | 87 (23.7) | 280 (76.3) | 1 | 1 | ||
>4 | 43 (57.3) | 32 (42.7) | 4.3 [2.6-7.3] | <0.001 | 4.4 [2.6-7.6] | <0.001 |
Pregnancy type | ||||||
Twin | 4 (8.2) | 45 (91.8) | 1 | 1 | ||
Singleton | 127 (32.1) | 269 (67.9) | 5.3 [1.9-15.1] | 0.002 | 3.5 [1.2-10.9] | 0.027 |
History of birth defect | ||||||
No | 125 (29.1) | 304 (70.9) | 1 | |||
Yes | 5 (38.5) | 8 (61.5) | 1.5 [0.5-4.7] | 0.470 | - | - |
Birth weight | ||||||
<2.5 kg | 26 (16.1) | 135 (83.9) | 1 | 1 | ||
≥2.5 kg | 105 (37.0) | 179 (63.0) | 3.0 [1.9-4.9] | <0.001 | 2.3 [1.4-3.9] | 0.002 |