From: Mitochondrial DNA association study of type 2 diabetes with or without ischemic stroke in Taiwan
Disease groups | Explanatory variables | Logistic regression | Fisher Exact test using SNPs between control and disease groups | |
---|---|---|---|---|
 |  | Gender, age, population and haplogroups (Control = 327 Desease = 481) | SNP markers from complete sequencing (Control= 73, T2Dall=103, T2Donly=70, T2DIS=33, IS= 63) | SNP markers from partial sequencing (Control= 327, Disease= 481) |
T2D With and without IS (T2Dall) | Gender | 0.67, 0.51~0.89** | 0.40, 0.21~0.74** | 0.61, 0.48~0.78*** |
Population | 1.7, 1.23~2.2*** | - | 1.7, 1.27~2.31*** | |
B4a1a | - | 3.93, 1.09~14.12* | - | |
B5a2b | - | - | 2.13, 1.07~4.24* | |
D | 0.53, 0.35~0.82** | - | 0.42, 0.24~0.74** | |
D4 | 0.35, 0.18~0.66*** | - | - | |
E1 | - | - | 1.95, 1.04~3.65* | |
F4b | - | - | 2.56, 1.23~5.34* | |
T2Donly | Population | 1.5, 1.1~2.0** | 2.71, 1.37~5.49** | 1.86, 1.36~2.55*** |
B4a1a | - | 3.83, 1.01~14.54* | - | |
B5a2b | 2.95, 1.23~7.05* | - | 2.38, 1.18~4.79* | |
D | 0.57, 0.37~0.90* | - | - | |
D4* | 0.36, 0.18~0.72* | 0.25, 0.07~0.93* | 0.32, 0.17~0.61*** | |
D5/M7 | - | - | 0.57, 0.33~0.98* | |
E | 1.89, 1.15~3.10* | 3.64, 1.25~10.64* | 1.86, 1.16~2.97** | |
E1a1 | - | 2.99, 1.09~8.22* | 1.86, 1.16~2.97** | |
E2b1 | 4.32, 1.36~13.72* | - | 1.86, 1.16~2.97** | |
F4b | - | - | 1.82, 1.03~3.22* | |
T2D with IS (T2DIS) | Gender | 0.52, 0.29~0.91* | 0.38, 0.16~0.89* | 0.44, 0.28~0.69*** |
Age | 1.06, 1.03~1.08*** | nt | nt | |
B4a1a | 3.90, 1.70~8.06*** | 5.19, 1.21~22.22* | 2.34, 1.04~5.30*, | |
B4c1b2 | 4.39, 1.50~12.80** | - | - | |
Ischemic Stroke (ISonly) | Gender | 0.51, 0.32~0.81** | 0.29, 0.14~0.58*** | 0.48, 0.32~0.71*** |
age | 1.10, 1.08~1.13*** | nt | nt | |
F4b | - | - | 3.09, 1.11~8.59* |