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Table 2 Microarray data gene ontology classifications

From: Butyrate induced changes in Wnt-signaling specific gene expression in colorectal cancer cells

Gene ontology

Microarray data gene ontology classifications

Categoryā€‰=ā€‰the name of the category within the ontology.

Ā Ā 

Genes in categoryā€‰=ā€‰the total number of genes in the genome that have been assigned to the category

Ā Ā 

Genes in list in categoryā€‰=ā€‰the total number of genes both in the selected gene list and in the category.

Ā Ā 

Biological process

Ā Ā 

Category

Genes in category

Genes in list in category

GO:50769: positive regulation of neurogenesis

101

14

GO:51094: positive regulation of development

420

30

GO:50793: regulation of development

848

49

GO:45598: regulation of fat cell differentiation

59

9

GO:50772: positive regulation of axonogenesis

47

8

GO:1779: natural killer cell differentiation

4

3

GO:9991: response to extracellular stimulus

238

19

GO:50767: regulation of neurogenesis

280

21

GO:45600: positive regulation of fat cell differentiation

20

5

GO:45444: fat cell differentiation

126

12

GO:30844: positive regulation of intermediate filament depolymerization

2

2

GO:45108: regulation of intermediate filament polymerization and/or depolymerization

2

2

GO:30842: regulation of intermediate filament depolymerization

2

2

GO:45106: intermediate filament depolymerization

2

2

GO:45105: intermediate filament polymerization and/or depolymerization

2

2

GO:48541: Peyerā€™s patch development

7

3

GO:50789: regulation of biological process

8048

292

GO:31667: response to nutrient levels

211

16

GO:1764: neuron migration

85

9

GO:48537: mucosal-associated lymphoid tissue development

8

3

GO:9892: negative regulation of metabolism

1238

58

GO:45595: regulation of cell differentiation

612

33

GO:51093: negative regulation of development

292

19

GO:6066: alcohol metabolism

576

31

GO:31324: negative regulation of cellular metabolism

1126

52

GO:31668: cellular response to extracellular stimulus

64

7

GO:30901: midbrain development

34

5

GO:48715: negative regulation of oligodendrocyte differentiation

11

3

GO:9912: auditory receptor cell fate commitment

4

2

GO:31670: cellular response to nutrient

4

2

GO:19221: cytokine and chemokine mediated signaling pathway

249

16

GO:42423: catecholamine biosynthesis

24

4

GO:1709: cell fate determination

38

5

GO:6260: DNA replication

343

20

GO:8089: anterograde axon cargo transport

13

3

GO:50768: negative regulation of neurogenesis

89

8

GO:30879: mammary gland development

39

5

GO:45773: positive regulation of axon extension

25

4

GO:45686: negative regulation of glial cell differentiation

25

4

GO:17085: response to insecticide

25

4

GO:50770: regulation of axonogenesis

91

8

GO:15879: carnitine transport

14

3

GO:19800: peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan

5

2

GO:48732: gland development

113

9

Cellular component

Ā Ā 

Category

Genes in category

Genes in list in category

GO:5622: intracellular

16495

558

GO:43229: intracellular organelle

13641

467

GO:43226: organelle

13647

467

GO:797: condensin core heterodimer

2

2

GO:43232: intracellular non-membrane-bound organelle

4379

168

GO:43228: non-membrane-bound organelle

4379

168

GO:796: condensin complex

9

3

GO:5856: cytoskeleton

2219

92

GO:15630: microtubule cytoskeleton

1021

48

GO:5813: centrosome

467

26

GO:118: histone deacetylase complex

72

7

GO:43231: intracellular membrane-bound organelle

12378

415

GO:43227: membrane-bound organelle

12386

415

GO:16272: prefoldin complex

14

3

GO:31618: nuclear centric heterochromatin

5

2

GO:5882: intermediate filament

223

14

Molecular function

Ā Ā 

Category

Genes in category

Genes in list in category

GO:5096: GTPase activator activity

397

25

GO:8118: N-acetyllactosaminide alpha-2,3-sialyltransferase activity

3

2

GO:16861: intramolecular oxidoreductase activity, interconverting aldoses and ketoses

11

3

GO:4873: asialoglycoprotein receptor activity

4

2

GO:8307: structural constituent of muscle

70

7

GO:8047: enzyme activator activity

573

30

GO:19894: kinesin binding

25

4

GO:31730: CCR5 chemokine receptor binding

5

2

GO:17123: Ral GTPase activator activity

5

2

  1. Clusters of genes whose expression is modulated as described in FigureĀ 3 and TableĀ 1, grouped into functionally relevant categories.