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Figure 1 | BMC Research Notes

Figure 1

From: A robust scoring system to evaluate sepsis severity in an animal model

Figure 1

Characterization of the FIP sepsis model in mice. (A) Mouse survival over time versus concentration of fecal solution (FS; n = 20 mice per concentration of FS). (B) Murine Sepsis Score (MSS) over time of mice that were administered 90 mg/mL FS (n = 20, 1 representative experiment). (C) Viable bacterial colony forming units (CFU) recovered from solid organs of mice treated with 90 mg/mL FS, at the time of euthanasia (n = 5). (D) Receiver-operator curve (ROC) evaluating the sensitivity and specificity of the MSS in differentiating healthy mice from those that progress to septic shock and death.

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