Deletions map with major clinical signs reported as coloured dots. Chromosome 11q arm ideogram with on the left gene density (from Ensemble http://www.ensembl.org/index.html) and, on the right, vertical bars are deletions reported in literature from the largest to the smallest. Red bar PC: present case. Green bars: family cases. Light blue bars: cases with molecularly defined deletions (13a and 13 b are family cases). The numbers above the bars correspond to those reported in Additional file 1: Table S1. Specific clinical signs are reported as coloured dots.