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Table 1 Univariate comparison between PCP positive and negative patients by presenting clinical and laboratory data

From: Pneumocystis pneumonia in South African children diagnosed by molecular methods

Variable PCP positive PCP negative p
  n = 109 n =93  
Presenting symptoms n (%)
Cough 94 (86.2) 78 (83.9) 0.6
Fever 30 (27.5) 47 (50.5) 0.0008
Poor feeding 28 (25.7) 21 (22.6) 0.6
Patient characteristics
Gender M:F 47:62 45:48 0.5
Age (Months) 3.4 (2.7 – 4.0) 2.2 (1.3 – 6.8) 0.03
HIV infected n (%) 87 (79.8) 37 (39.8) <0.0001
HIV exposed, uninfected 5 (4.6) 29 (31.2) <0.0001
Weight for age Z score −2.9 (−4.6 - -1.6) −2.4 (−3.9 - -1.36) 0.08
Height for age Z score −2.4 (−4.5 - -0.9) −2.3 (−3.2 - -0.9) 0.24
Duration of symptoms (days ) 3.0 (2.0 – 7.0) 3.0 (1.0 – 7.0) 0.66
Admission signs
Respiratory rate on admission (breaths per minute) 70.0 (60.0 – 80.0) 60.0 (50 – 70) 0.0002
Subcostal recessions n (%) 107 (98.2) 83 (89.2) 0.8
SpO2 (%) in room air (n = 146) 77.0 (65.5 – 84.0) 87.5 (75.0 – 92.0) <0.0001
Laboratory investigations
CD4% in HIV infected children 17.1 (9.9 – 29.7) 21.0 (14.7 – 29.7) 0.12
n = 80 n = 35
Lactate dehydrogenase (u/l) 710.5 (534.5 – 1067.0) 350.0 (238.0 – 610.0) <0.0001
  n = 57 n = 35  
  1. Continuous data are median (interquartile range).