Skip to main content
Figure 5 | BMC Research Notes

Figure 5

From: Central role for protein kinase C in oxytocin and epidermal growth factor stimulated cyclooxygenase 2 expression in human myometrial cells

Figure 5

Mechanisms of IL1β induced COX-2 expression in myometrial cells. Cells were stimulated with 5 ng/ml IL1β for 6 hours alone or in the presence of different inhibitors (2 μM TPCA-1, 2 μM PD-184352 and 5 μM BIS1). (A) Lysed cells were subjected to immunoblotting using a COX-2 antibody. Blots were stripped and re-probed for GAPDH. (B) COX-2 expression was normalised to GAPDH expression and given as a percentage of the IL1β treated value. Data points represent mean ± SEM, n = 5. Statistical significance was determined using one way ANOVA and Dunnett’s post hoc test. **P < 0.01 and ***P < 0.001.

Back to article page