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Table 1 Patient characteristics at the time of initial visit to a medical facility

From: Long-term survival of patients with pulmonary arterial hypertension recovering to World Health Organization functional class I or II: a historical comparison between intravenous epoprostenol and oral agents

Variables All Group 1 Group 2 Group 3 Group 4
Age (years) * 43 ± 22 38 ± 18 48 ± 22 52 ± 21 66 ± 9
Women/Men 34 (83) / 7 (17) 10 (24) / 0 (0) 6 (15) / 3 (7) 9 (22) / 0 (0) 9 (22) / 1 (2)
WHO-FC†§ II/III/IV 2(5) / 29(71) / 10(24) 0 (0) / 12 (29) / 1 (2) 0 (0) / 5 (12) / 4 (10) 2 (5) / 7 (17) / 0 (0) 0 (0) / 5 (12) / 5 (12)
Etiology Idiopathic 22(54) 9 (22) 6 (15) 2 (5) 5 (12)
Heritable 1(2) 0 (0) 0 (0) 1 (2) 0 (0)
CTD SSc 12(29) 1 (2) 3 (7) 4 (10) 4 (10)
MCTD 3(7) 2 (5) 0 (0) 1 (2) 0 (0)
SLE 2(5) 1 (2) 0 (0) 1 (2) 0 (0)
PM 1(2) 0 (0) 0 (0) 0 (0) 1 (2)
Hemodynamics* mPAP (mmHg) 51 ± 16 57 ± 21 53 ± 5 43 ± 13 45 ± 11
RAP (mmHg) 8 ± 6 6 ± 4|| 8 ± 4 6 ± 4# 14 ± 8||,#
CI (L/min/m2) 2.1 ± 0.6 2.1 ± 0.6 2.3 ± 0.5 1.9 ± 0.5 2.1 ± 0.6
PVR (dyne/sec/cm−5) 1058 ± 492 1368 ± 439 981 ± 314 884 ± 526 1039 ± 605
SvO2 (%) 60 ± 10 61 ± 9 50 ± 17 63 ± 9 60 ± 10
6MWD (m)*   196 ± 188 267 ± 164 150 ± 230 401 ± 39** 56 ± 106**
  1. *Average ± standard deviation, Number (%) of patients, p = 0.004 between Group 1 and 4, §p = 0.010, **p = 0.03 between Group 3 and 4, ||p = 0.02 between Group 1 and 4, #p = 0.02 between Group 3 and 4 in RAP. CI: cardiac index, CTD: connective tissue disease, MCTD: mixed connective tissue disease, mPAP: mean pulmonary arterial pressure, PM: polymyositis, PVR: pulmonary vascular resistance, RAP: right atrial pressure, SLE: systemic lupus erythematosus, SSc: scleroderma, SvO2: oxygen saturation of mixed venous blood, WHO-FC: World Health Organization functional class, 6MWD: 6-minute-walk distance.