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Table 2 Significant hits from association

From: Application of next generation sequencing to CEPH cell lines to discover variants associated with FDA approved chemotherapeutics

Drug(s) SNP ID SNP position Gene q-value MAF
Arsenic Trioxide rs60900828 (A/T) Chr16:56671632 MT1A (near-gene 5) 0.047628 0.138
Oxaliplatin rs562 (C/T) Chr3:183637845 ABCC5 (UTR3) 0.049494 0.392
  rs3749445 (A/G) Chr3:183638506 ABCC5 (UTR3) 0.044895 0.410
  rs2292998 (C/T) Chr3:183663833 ABCC5 (intronic) 0.039882 0.277
  rs1016752 (C/G) Chr3:183665062 ABCC5 (intronic) 0.039781 0.232
  rs4148585 (C/T) Chr3:183670642 ABCC5 (intronic) 0.039781 0.283
  rs6443924 (A/G) Chr3:183679532 ABCC5 (intronic) 0.039781 0.279
  rs4148579 (A/G) Chr3:183685249 ABCC5 (intronic) 0.039781 0.279
  rs939336 (A/G => C594C) Chr3:183685534 ABCC5 (exonic) 0.039781 0.279
  rs1132776 (C/T => A395A) Chr3:183696402 ABCC5 (exonic) 0.044895 0.289
  rs2313212 (C/T) Chr3:183700928 ABCC5 (intronic) 0.039781 0.279
  rs4148575 (C/T) Chr3:183702275 ABCC5 (UTR3) 0.044895 0.289
  rs1846692 (C/T) Chr16:56671696 MT1A (near - gene 5) 0.049494 0.360
  rs35346959 (A/G) Chr16:56671867 MT1A (near- gene 5) 0.044895 0.137
  rs9922957 (C/G) Chr16:56672380 MT1A (near - gene 5) 0.039781 0.185
  rs9922409 (A/G) Chr16:56672400 MT1A (near - gene 5) 0.04532 0.103
  rs7190725 (G/T) Chr16:56673290 MT1A (intronic) 0.044895 0.170
  rs8052394 (A/G => K51R) Chr16:56673828 MT1A (missense) 0.044895 0.152
  rs1800566 (C/T => P187S) chr16:69745145 NQO1 (exonic) 0.039781 0.258
  rs689455 (A/C) Chr16:69761661 NQO1 (near- gene 5) 0.039781 0.242
  1. Significant hits from association at FDR corrected threshold of 0.05 are shown in this table. All hits are known dbSNP common variants. All data is reported from Database of Single Nucleotide Polymorphisms (build 137).