Table 2 Significant hits from association
Drug(s) | SNP ID | SNP position | Gene | q-value | MAF |
|---|---|---|---|---|---|
Arsenic Trioxide | rs60900828 (A/T) | Chr16:56671632 | MT1A (near-gene 5) | 0.047628 | 0.138 |
Oxaliplatin | rs562 (C/T) | Chr3:183637845 | ABCC5 (UTR3) | 0.049494 | 0.392 |
rs3749445 (A/G) | Chr3:183638506 | ABCC5 (UTR3) | 0.044895 | 0.410 | |
rs2292998 (C/T) | Chr3:183663833 | ABCC5 (intronic) | 0.039882 | 0.277 | |
rs1016752 (C/G) | Chr3:183665062 | ABCC5 (intronic) | 0.039781 | 0.232 | |
rs4148585 (C/T) | Chr3:183670642 | ABCC5 (intronic) | 0.039781 | 0.283 | |
rs6443924 (A/G) | Chr3:183679532 | ABCC5 (intronic) | 0.039781 | 0.279 | |
rs4148579 (A/G) | Chr3:183685249 | ABCC5 (intronic) | 0.039781 | 0.279 | |
rs939336 (A/G => C594C) | Chr3:183685534 | ABCC5 (exonic) | 0.039781 | 0.279 | |
rs1132776 (C/T => A395A) | Chr3:183696402 | ABCC5 (exonic) | 0.044895 | 0.289 | |
rs2313212 (C/T) | Chr3:183700928 | ABCC5 (intronic) | 0.039781 | 0.279 | |
rs4148575 (C/T) | Chr3:183702275 | ABCC5 (UTR3) | 0.044895 | 0.289 | |
rs1846692 (C/T) | Chr16:56671696 | MT1A (near - gene 5) | 0.049494 | 0.360 | |
rs35346959 (A/G) | Chr16:56671867 | MT1A (near- gene 5) | 0.044895 | 0.137 | |
rs9922957 (C/G) | Chr16:56672380 | MT1A (near - gene 5) | 0.039781 | 0.185 | |
rs9922409 (A/G) | Chr16:56672400 | MT1A (near - gene 5) | 0.04532 | 0.103 | |
rs7190725 (G/T) | Chr16:56673290 | MT1A (intronic) | 0.044895 | 0.170 | |
rs8052394 (A/G => K51R) | Chr16:56673828 | MT1A (missense) | 0.044895 | 0.152 | |
rs1800566 (C/T => P187S) | chr16:69745145 | NQO1 (exonic) | 0.039781 | 0.258 | |
rs689455 (A/C) | Chr16:69761661 | NQO1 (near- gene 5) | 0.039781 | 0.242 |