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Table 1 Baseline demographic variables, disease features, and laboratory findings in patients with Crohn’s disease (CD) selected for color Doppler ultrasound evaluations of CD lesions in the small intestine

From: Doppler ultrasound findings correlate with tissue vascularity and inflammation in surgical pathology specimens from patients with small intestinal Crohn’s disease

Demography “Hypo-flow” “Hyper-flow” p value
  (n = 4) (n = 8)  
Age in years 40.0 ± 8.2 26.8 ± 13.8 0.1111)
Male (%) 2 (50.0) 3 (37.5) 1.0002)
CD duration in years 13.8 ± 7.8 3.9 ± 4.2 0.0811)
Previous segmental resection, % 0 0  
Disease location, n (%)*    0.4912)
L1 (distal 1/3 ileum ± limited cecal) 0 (0.0) 3 (37.5)  
L3 (ileocolonic) 4 (100.0) 5 (62.5)  
L4b (upper, distal to ligament of Treitz and proximal to distal 1/3 ileum) 0 (0.0) 0 (0.0)  
Disease behavior, n (%)*    
B1 (nonstricturing, nonpenetrating) 0 (0.0) 0 (0.0)  
B2 (stricturing) 4 (100.0) 8 (100.0)  
B3 (penetrating) 0 (0.0) 0 (0.0)  
B4 (structuring and penetrating) 0 (0.0) 0 (0.0)  
Primary indication for surgery, n (%)    1.0002)
Recurrence of obstruction symptoms 4 (100.0) 7 (87.5)  
Intractable disease 0 (0.0) 1 (12.5)  
CDAI 196.2 ± 73.8 198.2 ± 63.9 0.9631)
C reactive protein (mg/dl) 1.30 ± 2.01 0.47 ± 0.34 0.4661)
Erythorocyte sedimentation rate (mm/h) 32.0 ± 30.0 16.9 ± 14.3 0.2511)
Preoperative therapy, n (%)    
5ASA 4 (100.0) 5 (62.5) 0.4912)
Elemental diet (>900 kcal) 4 (100.0) 7 (87.5) 1.0002)
TPN 2 (50.0) 3 (37.5) 1.0002)
CS (prednisolone) 0 (0.0) 4 (50.0) 0.2082)
AZA/6MP 0 (0.0) 4 (50.0) 0.2082)
Anti-TNF-α biologics 1 (25.0) 0 (0.0) 0.3332)
Antibiotics 2 (50.0) 3 (37.5) 1.0002)
  1. 1)Student’s t-test; 2)Fisher’s exact test; *Paris classification of CD; CDAI, Crohn’s disease activity index (≥150 indicates active disease); 5ASA, 5-aminosalycilic acid; 6MP, 6-mercaptopurine; AZA, azathioprine; TPN, total parenteral nutrition.