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Table 1 Baseline demographic variables, disease features, and laboratory findings in patients with Crohn’s disease (CD) selected for color Doppler ultrasound evaluations of CD lesions in the small intestine

From: Doppler ultrasound findings correlate with tissue vascularity and inflammation in surgical pathology specimens from patients with small intestinal Crohn’s disease

Demography

“Hypo-flow”

“Hyper-flow”

p value

 

(n = 4)

(n = 8)

 

Age in years

40.0 ± 8.2

26.8 ± 13.8

0.1111)

Male (%)

2 (50.0)

3 (37.5)

1.0002)

CD duration in years

13.8 ± 7.8

3.9 ± 4.2

0.0811)

Previous segmental resection, %

0

0

 

Disease location, n (%)*

  

0.4912)

L1 (distal 1/3 ileum ± limited cecal)

0 (0.0)

3 (37.5)

 

L3 (ileocolonic)

4 (100.0)

5 (62.5)

 

L4b (upper, distal to ligament of Treitz and proximal to distal 1/3 ileum)

0 (0.0)

0 (0.0)

 

Disease behavior, n (%)*

   

B1 (nonstricturing, nonpenetrating)

0 (0.0)

0 (0.0)

 

B2 (stricturing)

4 (100.0)

8 (100.0)

 

B3 (penetrating)

0 (0.0)

0 (0.0)

 

B4 (structuring and penetrating)

0 (0.0)

0 (0.0)

 

Primary indication for surgery, n (%)

  

1.0002)

Recurrence of obstruction symptoms

4 (100.0)

7 (87.5)

 

Intractable disease

0 (0.0)

1 (12.5)

 

CDAI

196.2 ± 73.8

198.2 ± 63.9

0.9631)

C reactive protein (mg/dl)

1.30 ± 2.01

0.47 ± 0.34

0.4661)

Erythorocyte sedimentation rate (mm/h)

32.0 ± 30.0

16.9 ± 14.3

0.2511)

Preoperative therapy, n (%)

   

5ASA

4 (100.0)

5 (62.5)

0.4912)

Elemental diet (>900 kcal)

4 (100.0)

7 (87.5)

1.0002)

TPN

2 (50.0)

3 (37.5)

1.0002)

CS (prednisolone)

0 (0.0)

4 (50.0)

0.2082)

AZA/6MP

0 (0.0)

4 (50.0)

0.2082)

Anti-TNF-α biologics

1 (25.0)

0 (0.0)

0.3332)

Antibiotics

2 (50.0)

3 (37.5)

1.0002)

  1. 1)Student’s t-test; 2)Fisher’s exact test; *Paris classification of CD; CDAI, Crohn’s disease activity index (≥150 indicates active disease); 5ASA, 5-aminosalycilic acid; 6MP, 6-mercaptopurine; AZA, azathioprine; TPN, total parenteral nutrition.