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Table 1 Summary of whole smoke and GVP cytotoxicity results

From: Development of a BALB/c 3T3 neutral red uptake cytotoxicity test using a mainstream cigarette smoke exposure system

Airflow (L/min)

Log10airflow

Theoretical% smoke exposure

Theoretical nicotine exposure (mg)

Whole smoke

Gas vapour phase

% relative survival ± SD

Dilution IC50(L/min)

% smoke IC50

Theoretical nicotine exposure IC50(mg)

% Relative survival ± SD

Dilution IC50(L/min)

% smoke IC50

Theoretical nicotine exposure IC50(mg)

10.00

1.00

1.195

0.008

89.42 ± 13.22

6.02

1.99

0.014

100.22 ± 2.99

3.20

4.15

0.029

8.00

0.90

1.493

0.010

70.89 ± 25.21

101.43 ± 2.14

7.00

0.85

1.705

0.012

65.06 ± 15.38

90.97 ± 7.66

6.00*

0.78

1.987

0.014

46.90 ± 4.08

98.87 ± 4.33

5.00*

0.70

2.382

0.018

27.14 ± 11.91

75.57 ± 10.53

4.00*

0.60

2.973

0.021

4.08 ± 5.10

84.82 ± 8.07

3.00*

0.48

3.952

0.028

3.00 ± 8.60

44.38 ± 12.42

2.50

0.40

4.731

0.033

~

21.40 ± 6.58

2.00

0.30

5.892

0.041

~

12.13 ± 11.04

1.00

0.10

11.577

0.080

0.83 ± 7.28

8.65 ± 7.23

  1. Statistical difference denoted by*.