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Table 1 Summary of whole smoke and GVP cytotoxicity results

From: Development of a BALB/c 3T3 neutral red uptake cytotoxicity test using a mainstream cigarette smoke exposure system

Airflow (L/min) Log10airflow Theoretical% smoke exposure Theoretical nicotine exposure (mg) Whole smoke Gas vapour phase
% relative survival ± SD Dilution IC50(L/min) % smoke IC50 Theoretical nicotine exposure IC50(mg) % Relative survival ± SD Dilution IC50(L/min) % smoke IC50 Theoretical nicotine exposure IC50(mg)
10.00 1.00 1.195 0.008 89.42 ± 13.22 6.02 1.99 0.014 100.22 ± 2.99 3.20 4.15 0.029
8.00 0.90 1.493 0.010 70.89 ± 25.21 101.43 ± 2.14
7.00 0.85 1.705 0.012 65.06 ± 15.38 90.97 ± 7.66
6.00* 0.78 1.987 0.014 46.90 ± 4.08 98.87 ± 4.33
5.00* 0.70 2.382 0.018 27.14 ± 11.91 75.57 ± 10.53
4.00* 0.60 2.973 0.021 4.08 ± 5.10 84.82 ± 8.07
3.00* 0.48 3.952 0.028 3.00 ± 8.60 44.38 ± 12.42
2.50 0.40 4.731 0.033 ~ 21.40 ± 6.58
2.00 0.30 5.892 0.041 ~ 12.13 ± 11.04
1.00 0.10 11.577 0.080 0.83 ± 7.28 8.65 ± 7.23
  1. Statistical difference denoted by*.