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Table 2 Patient characteristics in relation to serum VEGF levels and IHC tissue staining of VEGF

From: Serum level and immunohistochemical expression of vascular endothelial growth factor for the prediction of postoperative recurrence in renal cell carcinoma

Characteristic

VEGF levels

 

IHC tissue staining of VEGF

(pg/mL)

 

Positive group

Negative group

 

Median [range]

P-value

n (%)

n (%)

P-value

Patient

  

26

57

 

Gender

     

 Male

314[42-1460]

 

13 (50)

39 (68)

 

 Female

290[52-912]

0.890

13 (50)

18 (32)

0.107

T stage

     

 T1

313[42-1330]

 

16 (65)

48 (84)

 

 T2

140[50-353]

 

4 (15)

1 (2)

 

 T3

294[79-1460]

 

6 (23)

8 (14)

 

 T4

-

0.109

0 (0)

0 (0)

0.023

Grade

     

 1

519[290-912]

 

1 (4)

6 (11)

 

 2

283[42-1460]

 

19 (73)

51 (89)

 

 3

385[225-982]

0.024

6 (23)

0 (0)

<0.001

UISS risk classification

     

 Low risk

313[42-1330]

 

14 (57)

47 (82)

 

 Intermediate risk

282[50-1460]

 

11 (42)

10 (18)

 

 High risk

982

0.282

1 (4)

0 (0)

0.014

Histological vein invasion

     

 No

325[42-1460]

 

15 (58)

38 (67)

 

 Yes

279[79-1330]

0.198

11 (42)

19 (33)

0.430

Tumor necrosis

     

 No

288[42-1460]

 

22 (85)

48 (84)

 

 Yes

405[93-982]

0.153

4 (15)

9 (16)

0.962

IHC staining

     

 Grade 0

313 [42-968]

 

-

-

 

 Grade 1+

325 [91-511]

 

-

-

 

 Grade 2+

248 [50-1460]

 

-

-

 

 Grade 3+

507 [140-1330]

0.378

-

-

 

Recurrence

     

 No

290[42-1460]

 

19 (73)

52 (91)

 

 Yes

478[140-982]

0.038

7 (27)

5 (9)

0.043