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Table 2 Spearman rank order coefficients of eNO and V’ NO with patient characteristics at birth and at day of measurements and lung function parameters

From: Effect of intubation and mechanical ventilation on exhaled nitric oxide in preterm infants with and without bronchopulmonary dysplasia measured at a median postmenstrual age of 49 weeks

  eNO (ppb) V’NO (nL/s)
  R s p-value R s p-value
Patient data at day of birth
Gestational age (weeks) -0.103 0.176 -0.058 0.447
Birth weight (g) -0.105 0.167 -0.045 0.555
Birth weight Z-score 0.033 0.666 0.049 0.515
Patient data at day of measurement
Age (days) 0.031 0.682 0.264 <0.001
PMA (weeks) -0.007 0.926 0.237 0.002
Body weight (g) -0.033 0.655 0.210 0.006
Body length (cm) 0.002 0.985 0.250 0.001
Tidal breathing     
VT (mL/kg) 0.011 0.883 0.151 0.047
RR (1/min) -0.216 0.004 -0.266 <0.001
V’E (mL/min/kg) -0.228 0.003 -0.170 0.025
tptef/te (%) -0.110 0.148 -0.113 0.135
te (s) 0.274 <0.001 0.281 <0.001
PTIF (mL/s/kg) -0.062 0.415 -0.083 0.272
PTEF (mL/s/kg) -0.230 0.002 -0.163 0.032
MTIF (mL/s/kg) -0.121 0.112 -0.107 0.158
MTEF (mL/s/kg) -0.274 <0.001 -0.192 0.011
Respiratory mechanics     
Crs (mL/kPa/kg) -0.027 0.725 0.058 0.450
Rrs (kPa/L/s) 0.078 0.318 -0.162 0.037
Blood gas analysis     
paO2 (mmHg) -0.059 0.434 0.147 0.053
paCO2 (mmHg) 0.158 0.037 -0.037 0.628
  1. R s , Spearman rank order correlation coefficient, statistically significant values after Bonferroni correction (p < 0.0025) are shown in boldface.
  2. Abbreviations: PMA - postmenstrual age, VT - tidal volume, RR - respiratory rate, V’E- minute ventilation, tptef/te - ratio of time to peak tidal expiratory flow to expiratory time, te - expiratory time, PTIF - peak tidal inspiratory flow, PTEF - peak tidal expiratory flow, MTIF - mean tidal inspiratory flow, MTEF - mean tidal expiratory flow, Crs - respiratory compliance, Rrs - respiratory resistance.