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Table 3 Effects of gene polymorphisms on plasma high-density lipoprotein (HDL)-cholesterol level in Y-consomic strains

From: Effect of the Y chromosome on plasma high-density lipoprotein-cholesterol levels in Y-chromosome-consomic mouse strains

SNP/Gene Polymorphism Plasma HDL-cholesterol level (mg/dl, mean ± SE) P value
rs46947134   C G   
(Uty)   (n = 132) (n = 39)   
   88.8 ± 0.9 95.7 ± 1.5   0.00046
Sry No. of CAG repeats starting at nt 8733 9 11 12  
(n = 64) (n = 68) (n = 39)  
   86.2 ± 1.2 91.3 ± 1.4 95.7 ± 1.5 4.73 × 10–5
Sry No. of CAG repeats starting at nt 8811 10 12 13  
(n = 39) (n = 109) (n = 23)  
   95.7 ± 1.5 88.7 ± 1.1 89.4 ± 1.9 NS (0.0021)2)
Sry Nts at nt 8491 and 8711 T C   
(n = 91) (n = 80)   
   92.6 ± 1.1 87.9 ± 1.2   NS (0.0050)
rs51766109   C T   
(Usp9y) (n = 52) (n = 119)   
   90.2 ± 1.5 90.5 ± 1.0   NS (0.90)
rs494688641)   A G   
(Usp9y) (n = 107) (n = 64)   
   92.9 ± 1.1 86.2 ± 1.2   5.27 × 10–5
  1. 1) In addition to rs49468864 in Usp9y, many SNPs showed a similar polymorphic pattern to rs49468864 [11].
  2. 2) NS: not significant.