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Table 3 Effects of gene polymorphisms on plasma high-density lipoprotein (HDL)-cholesterol level in Y-consomic strains

From: Effect of the Y chromosome on plasma high-density lipoprotein-cholesterol levels in Y-chromosome-consomic mouse strains

SNP/Gene

Polymorphism

Plasma HDL-cholesterol level (mg/dl, mean ± SE)

P value

rs46947134

 

C

G

  

(Uty)

 

(n = 132)

(n = 39)

  
  

88.8 ± 0.9

95.7 ± 1.5

 

0.00046

Sry

No. of CAG repeats starting at nt 8733

9

11

12

 

(n = 64)

(n = 68)

(n = 39)

 
  

86.2 ± 1.2

91.3 ± 1.4

95.7 ± 1.5

4.73 × 10–5

Sry

No. of CAG repeats starting at nt 8811

10

12

13

 

(n = 39)

(n = 109)

(n = 23)

 
  

95.7 ± 1.5

88.7 ± 1.1

89.4 ± 1.9

NS (0.0021)2)

Sry

Nts at nt 8491 and 8711

T

C

  

(n = 91)

(n = 80)

  
  

92.6 ± 1.1

87.9 ± 1.2

 

NS (0.0050)

rs51766109

 

C

T

  

(Usp9y)

(n = 52)

(n = 119)

  
  

90.2 ± 1.5

90.5 ± 1.0

 

NS (0.90)

rs494688641)

 

A

G

  

(Usp9y)

(n = 107)

(n = 64)

  
  

92.9 ± 1.1

86.2 ± 1.2

 

5.27 × 10–5

  1. 1) In addition to rs49468864 in Usp9y, many SNPs showed a similar polymorphic pattern to rs49468864 [11].
  2. 2) NS: not significant.