Table 1 Distribution and functions of beta adrenergic receptor
Subtype | Tissue distribution | Functions | Gene localization | Common functional variants |
|---|---|---|---|---|
BAR-2 | Lung, Brochial | Bronchodilation | 5q31-q32 | Arg16Gly |
Vascular smooth muscle | Vasodialation | Gln27Glu | ||
Heart | Positively inotropic and chronotropic | |||
Uterus | Relaxation | |||
Bladder | Relaxation | |||
Adipocytes | Lipolysis | |||
Eye | Increase aqueous humor | |||
Liver | Glycogenolysis | |||
Skeletal Muscle | Glycogenolysis | |||
Sympathetic terminal | Nor-epinephrine release |