Skip to main content

Table 3 Association between Arg16Gly and Gln27Glu polymorphisms of beta -2 adrenergic receptor and Ischemic stroke

From: Relationship between polymorphisms in beta -2 adrenergic receptor gene and ischemic stroke in North Indian Population: a hospital based case control study

Polymorphism N Sample Genotype distribution (%) HWE Recessive Dominant Sample Allele distribution (%) OR [95% CI],
       P value Adjusted Adjusted     P value
        OR [95% CI], OR [95% CI],     
Arg16Gly    Arg/Arg Arg/Gly Gly/Gly   P value P value   Arg Gly  
  224 IS 21 53 26 0.39 1.5 1.5 IS 47 53 1.3 [0.7 to 2.3],
  224 Controls 28 52 20 0.43 [0.76 to 3.2], [0.74 to 3.3], Control 54 46 0.32
        0.21 0.23     
  76 LVD 20 55 25 0.34 1.2 0.97 LVD 47 53 1.3 [0.7 to 2.3],
  224 Control 28 52 20 0.43 [0.21 to 7.6,] [0.07 to 13], Control 54 46 0.32
        0.78 0.98     
  78 SVD 19 50 31 0.88 2.9 2.4 SVD 44 56 1.4 [0.8 to 2.6],
  224 Control 28 52 20 0.43 [0.71 to 12], [0.43 to 13], Control 54 46 0.15
        0.13 0.31     
Gln27Glu    Gln/Gln Gln/Glu Glu/Glu      Gln Glu  
  224 IS 44 40 16 0.07 2.8 1.5 IS 64 36 1.6 [0.91 to 3.1],
  224 Controls 55 39 6 0.59 [0.98 to 8.1], [0.91 to 2.7], Control 75 25 0.09
        0.05 0.10     
  76 LVD 47 35 18 0.04 3.9 1.5 LVD 64 36 1.6 [0.91 to 3.1],
  224 Control 55 39 6 0.59 [1.3 to 11], [0.81 to 2.9], Control 75 25 0.09
        0.01 0.18     
  78 SVD 42 45 13 0.87 0.97 1.4 SVD 65 35 1.6 [ 0.87 to 2.9],
  224 Control 55 39 6 0.59 [0.15 to 6.1] [0.44 to 5], Control 75 25 0.12
        0.98 0.51     
  1. Abbreviations: IS ischemic stroke, OR odds ratio, CI confidence interval, LVD large vessel stroke, SVD small vessel stroke.