Table 5 Frequency distribution of variant allele of Arg16Gly and Gln27Glu polymorphism in few of different ethnic regions
Study design | Year | Allele frequency (%) | Population | Sample size | Condition | Reference | |
|---|---|---|---|---|---|---|---|
Gly16 | Glu27 | Case/control | |||||
Case/control | Case/control | ||||||
Case control | 1998 | NA | 0.43/0.36 | Denmark | 156/205 | Obesity | [21] |
Case control | 2006 | NA | 0.26/0.15 | Saudi Arabia | 773/528 | Coronary artery disease | [22] |
Case control | 2007 | 0.66/0.65 | 0.57/0.48 | Italy | 294/286 | Stroke | [20] |
Case control | 2011 | 0.46/0.43 | 0.17/0.14 | Chinese | 238/265 | Asthma | [23] |
Case control | 2012 | 0.49/0.39 | 0.07/0.12 | Malaysia | 50/50 | Hypertension | [24] |
Case control | 2005 | 0.40/0.38 | 0.43/0.41 | California | 194/819 | Myocardial infarction | [25] |
Cohort study | 2009 | 0.58 | 0.29 | Brazil | 501 | Heart Failure | [26] |
Meta-analysis | 2012 | 0.47/0.46 | 0.48/0.17 | Asian | 1097/844 | Chronic obstructive pulmonary disease | [27] |
Meta-analysis | 2012 | 0.61/0.62 | 0.41/0.40 | Caucasian | 727/850 | Chronic obstructive pulmonary disease | [27] |
Case control | 2012 | 0.60/0.65 | 0.27/0.30 | North Indian | 410/414 | Asthma | [28] |
Case control | 2014 | 0.52/0.58 | 0.47/0.23 | North Indian | 106/106 | Hemorrhagic Stroke | [29] |
Present study | 2014 | 0.53/0.46 | 0.36/0.25 | North Indian | 224/224 | Ischemic Stroke | Present study |