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Table 5 Frequency distribution of variant allele of Arg16Gly and Gln27Glu polymorphism in few of different ethnic regions

From: Relationship between polymorphisms in beta -2 adrenergic receptor gene and ischemic stroke in North Indian Population: a hospital based case control study

Study design Year Allele frequency (%) Population Sample size Condition Reference
Gly16 Glu27 Case/control
Case/control Case/control
Case control 1998 NA 0.43/0.36 Denmark 156/205 Obesity [21]
Case control 2006 NA 0.26/0.15 Saudi Arabia 773/528 Coronary artery disease [22]
Case control 2007 0.66/0.65 0.57/0.48 Italy 294/286 Stroke [20]
Case control 2011 0.46/0.43 0.17/0.14 Chinese 238/265 Asthma [23]
Case control 2012 0.49/0.39 0.07/0.12 Malaysia 50/50 Hypertension [24]
Case control 2005 0.40/0.38 0.43/0.41 California 194/819 Myocardial infarction [25]
Cohort study 2009 0.58 0.29 Brazil 501 Heart Failure [26]
Meta-analysis 2012 0.47/0.46 0.48/0.17 Asian 1097/844 Chronic obstructive pulmonary disease [27]
Meta-analysis 2012 0.61/0.62 0.41/0.40 Caucasian 727/850 Chronic obstructive pulmonary disease [27]
Case control 2012 0.60/0.65 0.27/0.30 North Indian 410/414 Asthma [28]
Case control 2014 0.52/0.58 0.47/0.23 North Indian 106/106 Hemorrhagic Stroke [29]
Present study 2014 0.53/0.46 0.36/0.25 North Indian 224/224 Ischemic Stroke Present study