Syndecan-3 and -4 expression in placenta. (A + C) mRNA expression, (B + D) Syndecan-3 and -4 protein expression. qPCR and Western blot analysis show differential expression patterns of syndecan-3 and -4 in human placenta samples from normal pregnant women (INT, interruptio; TERM, normal pregnancy, tissue sampled after birth) and women suffering from pregnancy complications (SA, spontaneous abortion; PE, pre-eclampsia). mRNA and proteins were isolated from snap frozen placenta samples. Expression was normalized to the house-keeping gene beta-actin. Each square represents one sample and data are presented as medians. Statistical differences between two groups were analyzed by the Mann–Whitney U-test. N.D., non-detectable. **p ≤ 0.01.