Figure 7
From: Computational prediction of disease microRNAs in domestic animals
Comparative structural analysis of human hsa-miR-143 and its animal orthologs. The multiple sequence alignment (A) shows the location of the mature miRNA on the 3′ arm of the pre-miRNA. The minimum free energy (MFE) secondary structure (B) of human mir-143 is compared to that of the animal orthologs and a normalized pre-miRNA consensus sequence. The species are abbreviated by their scientific names; hsa (Homo sapiens –human), ssc (Sus scrofa - pig), eca (Equine canibus - horse), and cfa (Canis familiaris - dog).