Expression of hepatic mRNAs following differentiation iPSC-K3aneuploidcells. Bar graph showing the relative levels of characteristic hepatic mRNAs identified by qRT-PCR in fresh human hepatocytes and in hepatocyte–like cells derived from iPSC-K3aneuploid (red bars) and control iPSC-K3 (parental; blue bars) cells. The level of mRNAs detected in primary human hepatocytes was set to 1 (black dashed line). Specific mRNA levels in all other samples are presented relative to primary human hepatocytes. Error bars represent the standard deviation recorded from five (n = 5) independent differentiation experiments and p ≤ 0.05 was considered significant (*).