Figure 2

Multiple alignment of 24 sequences of cleavage site (Hemagglutinin HA2). (Red line: sequence forming pathogenic cleavage site motif). Accession numbers: A/Chicken/Hong Kong/258/97(H5N1), AAC14418; A/equine/Miami/1963, AAA43164; A/equine/Nador/1/1997, AFJ69903; A/equine/Essaouira/2/2004, AFJ69905; A/equine/Essaouira/3/2004, AFJ69909; A/equine/Algiers/1/1972, ACF22126; A/equine/Italy/1199/1992 , ACD85308; A/equine/Otar/764/2007, ADZ55424; A/equine/Sachiyama/1/1971, ACI25735; A/equine/Sao Paulo/6/1963, ACD85264; A/equine/Egypt/6066NAMRU3-VSVRI/2008 (A/equine/Egypt/2008), ACH95682; A/equine/Uruguay/1/1963, ACD85418; A/equine/Tokyo/2/1971, AEM60147; A/equine/Sussex/1/1989, ACD97425; A/equine/Tiaret/1/2011, AGR54591; A/equine/Tiaret/2/2011, AGR54592; A/equine/Tiaret/3/2011, AGR54593; A/equine/Tiaret/4/2011, AGR54594; A/equine/Tiaret/5/2011, AGR54595; A/equine/Tiaret/6/2011, AGR54596 ;A/equine/Tiaret/7/2011, AGR54597 ; A/equine/Tiaret/8/2011 ,AGR54598; A/equine/Tiaret/9/2011, AGR54599; A/equine/Tiaret/10/2011, AGR54600.