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Table 3 Results of Spearman’s correlation showing the relationship between frequency of strains resistant to a particular antibiotic and consumption of antibiotics potentially showing selection pressure

From: Antibiotic consumption and its influence on the resistance in Enterobacteriaceae

Correlation 2000-2011

Statistical values

Consumption of antibiotics

Bacterial resistance

R

p

Fluoroquinolones

CIP

KLPN

0.0456

0.8797

  

ESCO

0.0105

0.9721

  

ENCL

-0.2355

0.4348

  

PRMI

-0.1965

0.5146

Third- and fourth-generation cephalosporins

CTZ

KLPN

0.2285

0.4486

  

ESCO

0.068

0.8216

  

ENCL

0.1439

0.6333

  

PRMI

-0.6139

0.0417

Third- and fourth-generation cephalosporins

PPT

KLPN

-0.1121

0.7101

  

ESCO

0.0437

0.8848

  

ENCL

-0.1329

0.6594

  

PRMI

-0.4804

0.1111

Third- and fourth-generation cephalosporins

CIP

KLPN

0.1053

0.727

  

ESCO

0.2285

0.4486

  

ENCL

-0.1371

0.6494

  

PRMI

0.1263

0.6753

Piperacillin/tazobactam

PPT

KLPN

0.8509

0.0048

  

ESCO

0.8421

0.052

  

ENCL

0.5009

0.0967

  

PRMI

-0.175

0.5617

Piperacillin/tazobactam

CTZ

KLPN

0.8398

0.0053

  

ESCO

0.8855

0.0033

  

ENCL

0.4921

0.1027

  

PRMI

0.0679

0.8218

Aminoglycosides

GEN

KLPN

0.6418

0.0333

  

ESCO

0.6964

0.0209

  

ENCL

0.523

0.0828

  

PRMI

-0.6702

0.0262

Aminoglycosides

AMI

KLPN

0.4135

0.1703

  

ESCO

0.7441

0.0136

  

ENCL

0.6307

0.0364

  

PRMI

-0.2708

0.369

  1. R – Spearman’s rank correlation coefficient, p - statistical significance.