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Table 3 Results of Spearman’s correlation showing the relationship between frequency of strains resistant to a particular antibiotic and consumption of antibiotics potentially showing selection pressure

From: Antibiotic consumption and its influence on the resistance in Enterobacteriaceae

Correlation 2000-2011 Statistical values
Consumption of antibiotics Bacterial resistance R p
Fluoroquinolones CIP KLPN 0.0456 0.8797
   ESCO 0.0105 0.9721
   ENCL -0.2355 0.4348
   PRMI -0.1965 0.5146
Third- and fourth-generation cephalosporins CTZ KLPN 0.2285 0.4486
   ESCO 0.068 0.8216
   ENCL 0.1439 0.6333
   PRMI -0.6139 0.0417
Third- and fourth-generation cephalosporins PPT KLPN -0.1121 0.7101
   ESCO 0.0437 0.8848
   ENCL -0.1329 0.6594
   PRMI -0.4804 0.1111
Third- and fourth-generation cephalosporins CIP KLPN 0.1053 0.727
   ESCO 0.2285 0.4486
   ENCL -0.1371 0.6494
   PRMI 0.1263 0.6753
Piperacillin/tazobactam PPT KLPN 0.8509 0.0048
   ESCO 0.8421 0.052
   ENCL 0.5009 0.0967
   PRMI -0.175 0.5617
Piperacillin/tazobactam CTZ KLPN 0.8398 0.0053
   ESCO 0.8855 0.0033
   ENCL 0.4921 0.1027
   PRMI 0.0679 0.8218
Aminoglycosides GEN KLPN 0.6418 0.0333
   ESCO 0.6964 0.0209
   ENCL 0.523 0.0828
   PRMI -0.6702 0.0262
Aminoglycosides AMI KLPN 0.4135 0.1703
   ESCO 0.7441 0.0136
   ENCL 0.6307 0.0364
   PRMI -0.2708 0.369
  1. R – Spearman’s rank correlation coefficient, p - statistical significance.