Figure 2From: Human plasma enhances the expression of Staphylococcal microbial surface components recognizing adhesive matrix molecules promoting biofilm formation and increases antimicrobial tolerance In VitroPlasma augmented biofilms have reduced susceptibility to vancomycin in vitro . A-B) Viability of bacteria (Log10 CFU/mL) within plasma augmented (MHB-10% Plasma, light bars) and non-augmented (MHB, dark bars) biofilms of a methicillin resistant (MRSA 3) and methicillin susceptible (UAMS-1) strain of S. aureus following overnight exposure to vancomycin (0, 2, 16, 128, and 1024 μg/mL). Bar graphs are indicative of the mean bacterial CFU ± SD. P-values generated via One-way ANOVA with a Dunnett’s post hoc test. C-D) SEM analysis of plasma and non-plasma augmented biofilms from the isolates listed above, following exposure to vancomycin. Images were captured at 2,500X. Size bars represent 10 μm.Back to article page