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Table 3 10% Plasma alters MSCRAMM gene expression in a strain dependent fashion

From: Human plasma enhances the expression of Staphylococcal microbial surface components recognizing adhesive matrix molecules promoting biofilm formation and increases antimicrobial tolerance In Vitro

Strain Gene Fold increase in gene expression*
   30 min 60 min 90 min 120 min
UAMS-1 Laminin binding protein (Eno) 1.62 2.06 2.76 3.39
  Encoding elastin binding protein (ebps) 3.42 2.98 4.61 3.50
  Fibrinogen binding protein (fib) 0.00 17.12 32.52 30.86
  Clumping factor A (clfA) 2.08 3.57 6.03 4.43
  Clumping factor B (clfB) 1.04 5.48 2.33 4.39
  Fibronectin binding protein (fbnA) 11.22 4.28 5.25 1.96
  Fibronectin binding protein (fbnB) 5.53 4.71 4.76 3.02
MRSA-1 Laminin binding protein (Eno) 1.51 2.15 2.85 2.51
  Encoding elastin binding protein (ebps) 1.11 1.29 2.02 1.75
  Fibrinogen binding protein (fib) 5.18 7.88 13.92 7.86
  Clumping factor A (clfA) 2.88 2.82 3.69 4.10
  Clumping factor B (clfB) 0.98 1.62 2.73 2.32
  Fibronectin binding protein (fbnA) 32.23 46.84 30.30 2.79
  Fibronectin binding protein (fbnB) 0.87 13.97 5.14 5.36
MRSA-2 Laminin binding protein (Eno) 1.06 3.53 3.83 3.63
  Encoding elastin binding protein (ebps) 1.01 3.80 2.12 1.38
  Fibrinogen binding protein (fib) 1.30 4.16 6.21 3.14
  Clumping factor A (clfA) 4.08 3.13 3.90 2.62
  Clumping factor B (clfB) 1.14 1.60 2.50 3.91
  Fibronectin binding protein (fbnA) 2.59 7.14 4.89 2.00
  Fibronectin binding protein (fbnB) 3.62 3.72 3.31 2.61
MRSA-3 Laminin binding protein (Eno) 1.31 1.86 3.96 2.95
  Encoding elastin binding protein (ebps) 0.99 1.21 3.67 1.88
  Fibrinogen binding protein (fib) 2.44 6.92 5.18 3.49
  Clumping factor A (clfA) 1.82 1.73 5.56 2.73
  Clumping factor B (clfB) 1.32 1.15 3.78 3.22
  Fibronectin binding protein (fbnA) 2.57 2.08 4.26 5.30
  Fibronectin binding protein (fbnB) 2.60 2.35 3.53 3.75
  1. *A greater than or equal to 3 fold increase was statistically significant (p<0.05) compared to baseline gene expression (t=0), and are indicated in boldface, One-way ANOVA with a Dunnet’s post hoc test.