Table 4 MGH-SFI item scores by ADT group and gender (safety sample)
MGH-SFI item | Bupropion plus aripiprazole, mean (SE) | SSRI/SNRI plus aripiprazole, mean (SE) | ||||
|---|---|---|---|---|---|---|
Baseline | Change from baseline at Week 52 (OC) | Change from baseline at Week 52 (LOCF) | Baseline | Change from baseline at Week 52 (OC) | Change from baseline at Week 52 (LOCF) | |
Males, n | 13 | 5 | 13 | 69 | 21 | 69 |
Interest in sex | 2.8 (0.3) | -0.2 (0.9) | 0.0 (0.4) | 3.8 (0.2) | -0.5 (0.4) | -0.3 (0.2) |
Ability to get sexually aroused | 3.1 (0.3) | 0.0 (0.8) | -0.1 (0.3) | 3.9 (0.2) | -0.8 (0.3) | -0.3 (0.2) |
Ability to achieve orgasm | 3.2 (0.4) | -0.4 (1.1) | -0.2 (0.4) | 4.0 (0.2) | -0.7 (0.4) | -0.4 (0.2) |
Ability to get erection | 3.7 (0.4) | -1.2 (0.4) | -0.6 (0.2) | 3.7 (0.2) | -0.3 (0.4) | -0.2 (0.2) |
Overall sexual satisfaction | 3.9 (0.4) | -1.4 (0.2) | -0.7 (0.3) | 4.1 (0.2) | -0.6 (0.3) | -0.4 (0.2) |
Females, n | 24 | 14 | 24 | 147 | 48 | 147 |
Interest in sex | 3.9 (0.3) | -0.5 (0.3) | -0.5 (0.3) | 4.6 (0.1) | -0.9 (0.2) | -0.9 (0.1) |
Ability to get sexually aroused | 4.0 (0.3) | -0.4 (0.5) | -0.5 (0.3) | 4.6 (0.1) | -0.9 (0.2) | -0.7 (0.1) |
Ability to achieve orgasm | 3.9 (0.4) | -0.3 (0.5) | -0.3 (0.3) | 4.6 (0.1) | -0.8 (0.2) | -0.7 (0.1) |
Overall sexual satisfaction | 4.1 (0.3) | -0.8 (0.4) | -0.7 (0.3) | 4.7 (0.1) | -1.1 (0.2) | -0.8 (0.1) |