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Table 1 Case reports of lymphoma in patients with metal implants

From: Large B-cell lymphoma mimicking iliopsoas abscess following open revision of proximal femur infected non-union: a case report

Author, year

Age (years)/Gender

Implant

Time to presentation (years)

Symptoms

Diagnosis

Treatment

McDonald [17], 1981

48/M

Cobalt chromium plate and screws in tibia

17 years

Aching, night sweats, malaise

Histiocytic lymphoma

Chemotherapy and Radiotherapy

Dodion et al. [18], 1983

50/M

Cobalt chromium screw and plate

14 months

Local pain

Diffuse Large B-cell lymphoma

Chemotherapy and Radiotherapy

Syed et al. [19], 1997

75/F

Exeter Hip Replacement

7 years

Increasing thigh and groin pain with inability to weight bear

Non-Hodgkins Lymphoma

Radiotherapy

Rahdi et al. [10], 1998

25/M

Internal fixation of distal tibia

8 years

Slow growing ankle mass

Diffuse Large B-cell lymphoma

Chemotherapy, Below-knee amputation

Rahdi et al. [10], 1998

64/F

Primary Total Hip

4 years

6 month history of pain and swelling in thigh

Diffuse Large B-cell lymphoma

Chemotherapy and Radiotherapy

Ito et al. [20], 1999

80/F

Primary Total Hip

8 years

Pain in hip

Diffuse Large B-cell lymphoma

Radiotherapy

Ganapathi et al. [21], 2001

85/M

Primary Total Hip, Revision Total Hip

12 years post THA, 10 years post revision, 14 mo post periprosthetic fracture

Chronic draining sinus, anorexia, lethargy, drowsiness

Diffuse Large B-cell lymphoma

Died prior to radiotherapy

O’Shea et al. [22], 2006

75/F

Primary Total Hip

13 years

Chronic draining sinus, pain and swelling of thigh

Diffuse Large B-cell lymphoma

Chemotherapy, radiotherapy, excision arthroplasty

Hsieh et al. [23], 2007

30/F

Primary Total Hip

4 years post

3 month history of hip pain

Diffuse Large B-cell lymphoma

Chemotherapy

Cheuk et al. [24], 2008

78/M

Primary Total Hip, Revision × 2

32 years post primary TKR, 16 years post revision

Increasing knee pain

Diffuse Large B-cell lymphoma

Radiotherapy

Eskander et al. [25], 2008

70/F

Primary Total Knee

1 year

Two superficial areas of skin necrosis as well as surrounding ecchymosis and edema

Diffuse Large B-cell lymphoma

Radiotherapy, knee fusion

Palraj et al. [26], 2010

77/M

Stainless screw plate and screws for tibial fracture

7 years

2 weeks of pain and erythema, localized swelling, minimal warmth

Anaplastic T-cell lymphoma

Chemotherapy

Chaudhry et al. [27], 2011

76/M

Primary Total Knee

3 years

1 week history of knee pain

Diffuse Large B-cell lymphoma

Chemotherapy and Radiotherapy

  1. Abbreviations: M male, F female, TKR total knee replacement, THA total hip arthroplasty.