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Table 1 Case reports of lymphoma in patients with metal implants

From: Large B-cell lymphoma mimicking iliopsoas abscess following open revision of proximal femur infected non-union: a case report

Author, year Age (years)/Gender Implant Time to presentation (years) Symptoms Diagnosis Treatment
McDonald [17], 1981 48/M Cobalt chromium plate and screws in tibia 17 years Aching, night sweats, malaise Histiocytic lymphoma Chemotherapy and Radiotherapy
Dodion et al. [18], 1983 50/M Cobalt chromium screw and plate 14 months Local pain Diffuse Large B-cell lymphoma Chemotherapy and Radiotherapy
Syed et al. [19], 1997 75/F Exeter Hip Replacement 7 years Increasing thigh and groin pain with inability to weight bear Non-Hodgkins Lymphoma Radiotherapy
Rahdi et al. [10], 1998 25/M Internal fixation of distal tibia 8 years Slow growing ankle mass Diffuse Large B-cell lymphoma Chemotherapy, Below-knee amputation
Rahdi et al. [10], 1998 64/F Primary Total Hip 4 years 6 month history of pain and swelling in thigh Diffuse Large B-cell lymphoma Chemotherapy and Radiotherapy
Ito et al. [20], 1999 80/F Primary Total Hip 8 years Pain in hip Diffuse Large B-cell lymphoma Radiotherapy
Ganapathi et al. [21], 2001 85/M Primary Total Hip, Revision Total Hip 12 years post THA, 10 years post revision, 14 mo post periprosthetic fracture Chronic draining sinus, anorexia, lethargy, drowsiness Diffuse Large B-cell lymphoma Died prior to radiotherapy
O’Shea et al. [22], 2006 75/F Primary Total Hip 13 years Chronic draining sinus, pain and swelling of thigh Diffuse Large B-cell lymphoma Chemotherapy, radiotherapy, excision arthroplasty
Hsieh et al. [23], 2007 30/F Primary Total Hip 4 years post 3 month history of hip pain Diffuse Large B-cell lymphoma Chemotherapy
Cheuk et al. [24], 2008 78/M Primary Total Hip, Revision × 2 32 years post primary TKR, 16 years post revision Increasing knee pain Diffuse Large B-cell lymphoma Radiotherapy
Eskander et al. [25], 2008 70/F Primary Total Knee 1 year Two superficial areas of skin necrosis as well as surrounding ecchymosis and edema Diffuse Large B-cell lymphoma Radiotherapy, knee fusion
Palraj et al. [26], 2010 77/M Stainless screw plate and screws for tibial fracture 7 years 2 weeks of pain and erythema, localized swelling, minimal warmth Anaplastic T-cell lymphoma Chemotherapy
Chaudhry et al. [27], 2011 76/M Primary Total Knee 3 years 1 week history of knee pain Diffuse Large B-cell lymphoma Chemotherapy and Radiotherapy
  1. Abbreviations: M male, F female, TKR total knee replacement, THA total hip arthroplasty.