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Table 4 Comparison with PCA-GPCR and HMM-ModE/HMMER2 [9] to classify D1238 and D365 dataset

From: HMM-ModE: implementation, benchmarking and validation with HMMER3

Dataset Sub-family Total Predicted Accuracy
This paper [9] [23]
D1238 Rhodopsin like 1103 1030 93.38 95.10 99.91
Secretin like 84 66 78.57 78.57 98.81
Metabotropic/glutamate/pheromone 51 47 92.15 60.78 98.04
D365 Rhodopsin like 232 200 86.20 87.50 95.69
Secretin like 39 23 58.97 58.97 87.18
Metabotropic/glutamate/pheromone 44 34 77.27 54.54 88.64
Fungal Pheromone 23 23 100 78.26 95.65
CAMP receptors 10 10 100 100 100
Frizzled/smoothened 17 17 100 100 64.71
  1. The accuracy values for the method PCA-GPCR are directly taken from their article. The data in bold depicts the results using HMM-ModE with HMMER3 and HMMER2.