HMM-ModE: implementation, benchmarking and validation with HMMER3

BMC Research Notes

Table 5 This table shows the performance of our method, HMM-ModE/HMMER2 [9] and PCA_GPCR on GPCR_human dataset

Sub-family	Total	Predicted	Accuracy
Sub-family	Total	Predicted	This paper	[9]	[23]
Muscarinic acetylcholine	11	11	100	100	100
Adrenocceptors	24	23	95.83	95.83	95.83
Dopamine	17	16	94.11	94.11	94.11
Histamine	16	16	100	100	75.00
Serotonin	26	25	96.15	96.15	76.92
Trace amine	23	14	60.87	60.87	78.26

“Total” is the number of sequences present in a sub-family. The data in bold depicts the results using HMM-ModE with HMMER3 and HMMER2.

ISSN: 1756-0500