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Table 1 MIC distributions and intra laboratory variations for isoniazid (INH), amikacin (AMK) and ofloxacin (OFL)

From: A 24-well plate assay for simultaneous testing of first and second line drugs against Mycobacterium tuberculosis in a high endemic setting

Test batch

MIC (μg/ml) for H37Rv

MIC (μg/ml) for the QC MDR strain

 

INH

AMK

OFL

INH

AMK

OFL

01

0.125

0.5

0.5

ND

ND

ND

02

0.125

0.5

0.5

ND

ND

ND

03

0.125

0.5

0.5

1.0

1.0

1.0

04

0.125

0.5

0.5

>1.0

1.0

1.0

05

0.125

0.5

1.0

>1.0

1.0

1.0

06

0.125

0.5

1.0

>1.0

1.0

1.0

07

0.125

0.5

1.0

>1.0

1.0

1.0

08

0.125

0.5

0.5

>1.0

1.0

1.0

09

0.125

0.5

0.5

>1.0

1.0

1.0

10

0.2

0.5

0.5

>1.0

1.0

1.0

11

0.2

0.5

0.5

>1.0

1.0

1.0

12

0.125

0.5

0.5

>1.0

1.0

1.0

13

0.125

0.5

0.5

>1.0

1.0

1.0

  1. (ND, no data; QC = Quality control).