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Table 2 Cellular processes of genes associated with poor prognosis

From: Analysis of high fat diet induced genes during mammary gland development: identifying role players in poor prognosis of breast cancer

Gene Description GO reference Gene ontology
Mmp12 Matrix metallopeptidase 12 GO:0006508 Proteolysis
Gpnmb Glycoprotein (transmembrane) GO: 0007155 Cell adhesion
Ctsl Cathepsin L GO:0006508 Proteolysis
Lilrb4 Leukocyte immunoglobulin-like receptor, subfamily B, member 4 GO: 0045671 Negative regulation of osteoclast differentiation
Dnmt3a DNA (cytosine-5-)-methyltransferase 3 alpha GO:0006306 DNA methylation
Slc11a1 Solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 GO:0070839 Divalent metal ion export
Ncf2 Neutrophil cytosolic factor 2 GO:0016175 Superoxide-generating NADPH oxidase activity
Ptpns1 Signal-regulatory protein alpha GO: 0007155 Cell adhesion
Itgb2 Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) GO:0007155 Cell adhesion
Cstb Cystatin B (stefin B) GO:0010466 Negative regulation of peptidase activity
Ppgb1 Cathepsin A GO: 0006508 Proteolysis
Adam8 ADAM metallopeptidase domain 8 GO: 0006508 Proteolysis
Fcgr3 Fc fragment of IgG, low affinity IIIa, receptor (CD16a) GO:0001788 Antibody-dependent cellular cytotoxicity
  1. Gene ontologies from the AMIGO database were obtained for HFD induced genes that were found to be associated with poor prognosis.